Accession number: PF00042 |
Blosum Log2 No Clustering |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 2 | 1 | 0 | 0 | -2 | 1 | -1 | -1 | 0 | -2 | -1 | -1 | 0 | 0 | 0 | 1 | 0 | -1 | -3 | -1 |
| C | 1 | 5 | -1 | -1 | -1 | 0 | -2 | 1 | -2 | 0 | 0 | -1 | -2 | -2 | -2 | 0 | 0 | 1 | -2 | -2 |
| D | 0 | -1 | 3 | 2 | -5 | 0 | -1 | -4 | 0 | -4 | -2 | 2 | 1 | 1 | 0 | 1 | 1 | -2 | -2 | -2 |
| E | 0 | -1 | 2 | 2 | -4 | 0 | -1 | -2 | 1 | -3 | -2 | 1 | 0 | 1 | 0 | 0 | 0 | -1 | -3 | -2 |
| F | -2 | -1 | -5 | -4 | 5 | -3 | -4 | 0 | -4 | 1 | 1 | -3 | -5 | -4 | -3 | -4 | -3 | 0 | 2 | 1 |
| G | 1 | 0 | 0 | 0 | -3 | 4 | -1 | -3 | 0 | -2 | -2 | 0 | 1 | 0 | 0 | 1 | 0 | -2 | -3 | -2 |
| H | -1 | -2 | -1 | -1 | -4 | -1 | 6 | -4 | 0 | -2 | -2 | 1 | -2 | 1 | 0 | -1 | -1 | -2 | -7 | 1 |
| I | -1 | 1 | -4 | -2 | 0 | -3 | -4 | 3 | -2 | 2 | 2 | -2 | -4 | -3 | -2 | -1 | 0 | 3 | -3 | -1 |
| K | 0 | -2 | 0 | 1 | -4 | 0 | 0 | -2 | 3 | -2 | -1 | 0 | 0 | 1 | 2 | 0 | 0 | -2 | -4 | -1 |
| L | -2 | 0 | -4 | -3 | 1 | -2 | -2 | 2 | -2 | 3 | 2 | -2 | -4 | -2 | -2 | -2 | -1 | 1 | 0 | 1 |
| M | -1 | 0 | -2 | -2 | 1 | -2 | -2 | 2 | -1 | 2 | 3 | -2 | -3 | -1 | 0 | -2 | -1 | 1 | 1 | 1 |
| N | -1 | -1 | 2 | 1 | -3 | 0 | 1 | -2 | 0 | -2 | -2 | 3 | -1 | 1 | 0 | 1 | 1 | -1 | -5 | 1 |
| P | 0 | -2 | 1 | 0 | -5 | 1 | -2 | -4 | 0 | -4 | -3 | -1 | 7 | -1 | -2 | 0 | -1 | -3 | -4 | -4 |
| Q | 0 | -2 | 1 | 1 | -4 | 0 | 1 | -3 | 1 | -2 | -1 | 1 | -1 | 2 | 1 | 0 | 0 | -2 | -4 | -1 |
| R | 0 | -2 | 0 | 0 | -3 | 0 | 0 | -2 | 2 | -2 | 0 | 0 | -2 | 1 | 4 | 0 | 0 | -2 | -3 | -1 |
| S | 1 | 0 | 1 | 0 | -4 | 1 | -1 | -1 | 0 | -2 | -2 | 1 | 0 | 0 | 0 | 2 | 1 | -2 | -3 | -1 |
| T | 0 | 0 | 1 | 0 | -3 | 0 | -1 | 0 | 0 | -1 | -1 | 1 | -1 | 0 | 0 | 1 | 2 | 0 | -3 | 0 |
| V | -1 | 1 | -2 | -1 | 0 | -2 | -2 | 3 | -2 | 1 | 1 | -1 | -3 | -2 | -2 | -2 | 0 | 3 | -1 | 0 |
| W | -3 | -2 | -2 | -3 | 2 | -3 | -7 | -3 | -4 | 0 | 1 | -5 | -4 | -4 | -3 | -3 | -3 | -1 | 9 | 0 |
| Y | -1 | -2 | -2 | -2 | 1 | -2 | 1 | -1 | -1 | 1 | 1 | 1 | -4 | -1 | -1 | -1 | 0 | 0 | 0 | 5 |
Blosum LN No Clustering |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1 | 1 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | -1 | -1 | -1 | 0 | 0 | 0 | 1 | 0 | 0 | -2 | -1 |
| C | 1 | 4 | -1 | -1 | 0 | 0 | -1 | 1 | -1 | 0 | 0 | 0 | -1 | -1 | -1 | 0 | 0 | 1 | -1 | -1 |
| D | 0 | -1 | 2 | 1 | -3 | 0 | -1 | -3 | 0 | -3 | -2 | 1 | 0 | 1 | 0 | 1 | 1 | -2 | -2 | -1 |
| E | 0 | -1 | 1 | 2 | -3 | 0 | -1 | -2 | 0 | -2 | -1 | 0 | 0 | 1 | 0 | 0 | 0 | -1 | -2 | -1 |
| F | -1 | 0 | -3 | -3 | 4 | -2 | -2 | 0 | -3 | 1 | 1 | -2 | -3 | -3 | -2 | -2 | -2 | 0 | 1 | 1 |
| G | 0 | 0 | 0 | 0 | -2 | 3 | -1 | -2 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | 1 | 0 | -1 | -2 | -1 |
| H | -1 | -1 | -1 | -1 | -2 | -1 | 4 | -2 | 0 | -1 | -2 | 0 | -2 | 1 | 0 | -1 | -1 | -2 | -5 | 1 |
| I | 0 | 1 | -3 | -2 | 0 | -2 | -2 | 2 | -1 | 1 | 1 | -1 | -3 | -2 | -1 | -1 | 0 | 2 | -2 | -1 |
| K | 0 | -1 | 0 | 0 | -3 | 0 | 0 | -1 | 2 | -2 | -1 | 0 | 0 | 1 | 2 | 0 | 0 | -1 | -3 | -1 |
| L | -1 | 0 | -3 | -2 | 1 | -1 | -1 | 1 | -2 | 2 | 1 | -1 | -3 | -2 | -2 | -2 | -1 | 1 | 0 | 1 |
| M | -1 | 0 | -2 | -1 | 1 | -1 | -2 | 1 | -1 | 1 | 2 | -1 | -2 | -1 | 0 | -1 | -1 | 1 | 1 | 1 |
| N | -1 | 0 | 1 | 0 | -2 | 0 | 0 | -1 | 0 | -1 | -1 | 2 | -1 | 1 | 0 | 1 | 1 | -1 | -3 | 0 |
| P | 0 | -1 | 0 | 0 | -3 | 0 | -2 | -3 | 0 | -3 | -2 | -1 | 5 | 0 | -2 | 0 | -1 | -2 | -3 | -3 |
| Q | 0 | -1 | 1 | 1 | -3 | 0 | 1 | -2 | 1 | -2 | -1 | 1 | 0 | 2 | 1 | 0 | 0 | -1 | -3 | -1 |
| R | 0 | -1 | 0 | 0 | -2 | 0 | 0 | -1 | 2 | -2 | 0 | 0 | -2 | 1 | 3 | 0 | 0 | -1 | -2 | -1 |
| S | 1 | 0 | 1 | 0 | -2 | 1 | -1 | -1 | 0 | -2 | -1 | 1 | 0 | 0 | 0 | 2 | 1 | -1 | -2 | -1 |
| T | 0 | 0 | 1 | 0 | -2 | 0 | -1 | 0 | 0 | -1 | -1 | 1 | -1 | 0 | 0 | 1 | 1 | 0 | -2 | 0 |
| V | 0 | 1 | -2 | -1 | 0 | -1 | -2 | 2 | -1 | 1 | 1 | -1 | -2 | -1 | -1 | -1 | 0 | 2 | -1 | 0 |
| W | -2 | -1 | -2 | -2 | 1 | -2 | -5 | -2 | -3 | 0 | 1 | -3 | -3 | -3 | -2 | -2 | -2 | -1 | 7 | 0 |
| Y | -1 | -1 | -1 | -1 | 1 | -1 | 1 | -1 | -1 | 1 | 1 | 0 | -3 | -1 | -1 | -1 | 0 | 0 | 0 | 3 |
Blosum Log10 No Clustering |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 |
| C | 0 | 2 | 0 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | -1 | -1 | -1 | 0 | 0 | 0 | -1 | 0 |
| D | 0 | 0 | 1 | 1 | -1 | 0 | 0 | -1 | 0 | -1 | -1 | 1 | 0 | 0 | 0 | 0 | 0 | -1 | -1 | -1 |
| E | 0 | 0 | 1 | 1 | -1 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 |
| F | -1 | 0 | -1 | -1 | 2 | -1 | -1 | 0 | -1 | 0 | 0 | -1 | -1 | -1 | -1 | -1 | -1 | 0 | 1 | 0 |
| G | 0 | 0 | 0 | 0 | -1 | 1 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | -1 | -1 |
| H | 0 | -1 | 0 | 0 | -1 | 0 | 2 | -1 | 0 | -1 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | -1 | -2 | 0 |
| I | 0 | 0 | -1 | -1 | 0 | -1 | -1 | 1 | -1 | 1 | 1 | -1 | -1 | -1 | -1 | 0 | 0 | 1 | -1 | 0 |
| K | 0 | -1 | 0 | 0 | -1 | 0 | 0 | -1 | 1 | -1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | -1 | -1 | 0 |
| L | 0 | 0 | -1 | -1 | 0 | -1 | -1 | 1 | -1 | 1 | 1 | -1 | -1 | -1 | -1 | -1 | 0 | 0 | 0 | 0 |
| M | 0 | 0 | -1 | 0 | 0 | 0 | -1 | 1 | 0 | 1 | 1 | -1 | -1 | 0 | 0 | -1 | 0 | 0 | 0 | 0 |
| N | 0 | 0 | 1 | 0 | -1 | 0 | 0 | -1 | 0 | -1 | -1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 |
| P | 0 | -1 | 0 | 0 | -1 | 0 | -1 | -1 | 0 | -1 | -1 | 0 | 2 | 0 | -1 | 0 | 0 | -1 | -1 | -1 |
| Q | 0 | -1 | 0 | 0 | -1 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | -1 | 0 |
| R | 0 | -1 | 0 | 0 | -1 | 0 | 0 | -1 | 1 | -1 | 0 | 0 | -1 | 0 | 1 | 0 | 0 | 0 | -1 | 0 |
| S | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | 1 | 0 | -1 | -1 | 0 |
| T | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | -1 | 0 |
| V | 0 | 0 | -1 | 0 | 0 | -1 | -1 | 1 | -1 | 0 | 0 | 0 | -1 | 0 | 0 | -1 | 0 | 1 | 0 | 0 |
| W | -1 | -1 | -1 | -1 | 1 | -1 | -2 | -1 | -1 | 0 | 0 | -1 | -1 | -1 | -1 | -1 | -1 | 0 | 3 | 0 |
| Y | 0 | 0 | -1 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Distance Log2 |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 4 | 7 | 5 | 5 | 6 | 5 | 6 | 6 | 5 | 5 | 7 | 6 | 6 | 6 | 6 | 5 | 5 | 5 | 9 | 7 |
| C | 7 | 10 | 9 | 9 | 9 | 9 | 10 | 8 | 9 | 8 | 10 | 10 | 11 | 10 | 10 | 9 | 9 | 8 | 11 | 11 |
| D | 5 | 9 | 6 | 5 | 9 | 6 | 7 | 8 | 6 | 8 | 9 | 6 | 7 | 6 | 7 | 6 | 6 | 7 | 9 | 8 |
| E | 5 | 9 | 5 | 6 | 8 | 6 | 7 | 8 | 6 | 7 | 9 | 7 | 7 | 6 | 7 | 6 | 6 | 7 | 9 | 8 |
| F | 6 | 9 | 9 | 8 | 4 | 8 | 8 | 6 | 8 | 5 | 7 | 8 | 9 | 9 | 8 | 8 | 8 | 6 | 7 | 7 |
| G | 5 | 9 | 6 | 6 | 8 | 5 | 7 | 8 | 6 | 6 | 9 | 7 | 7 | 7 | 7 | 6 | 7 | 7 | 9 | 8 |
| H | 6 | 10 | 7 | 7 | 8 | 7 | 5 | 9 | 6 | 7 | 9 | 7 | 9 | 7 | 8 | 7 | 8 | 7 | 12 | 8 |
| I | 6 | 8 | 8 | 8 | 6 | 8 | 9 | 6 | 7 | 5 | 7 | 8 | 10 | 8 | 8 | 7 | 7 | 5 | 10 | 8 |
| K | 5 | 9 | 6 | 6 | 8 | 6 | 6 | 7 | 5 | 6 | 8 | 6 | 7 | 6 | 5 | 6 | 6 | 6 | 10 | 8 |
| L | 5 | 8 | 8 | 7 | 5 | 6 | 7 | 5 | 6 | 4 | 6 | 7 | 8 | 7 | 7 | 7 | 6 | 5 | 7 | 6 |
| M | 7 | 10 | 9 | 9 | 7 | 9 | 9 | 7 | 8 | 6 | 9 | 9 | 10 | 9 | 9 | 9 | 9 | 7 | 9 | 9 |
| N | 6 | 10 | 6 | 7 | 8 | 7 | 7 | 8 | 6 | 7 | 9 | 7 | 8 | 7 | 7 | 6 | 7 | 7 | 11 | 8 |
| P | 6 | 11 | 7 | 7 | 9 | 7 | 9 | 10 | 7 | 8 | 10 | 8 | 6 | 8 | 9 | 7 | 8 | 8 | 11 | 11 |
| Q | 6 | 10 | 6 | 6 | 9 | 7 | 7 | 8 | 6 | 7 | 9 | 7 | 8 | 7 | 7 | 7 | 7 | 7 | 11 | 9 |
| R | 6 | 10 | 7 | 7 | 8 | 7 | 8 | 8 | 5 | 7 | 9 | 7 | 9 | 7 | 7 | 7 | 7 | 7 | 10 | 9 |
| S | 5 | 9 | 6 | 6 | 8 | 6 | 7 | 7 | 6 | 7 | 9 | 6 | 7 | 7 | 7 | 6 | 6 | 7 | 9 | 8 |
| T | 5 | 9 | 6 | 6 | 8 | 7 | 8 | 7 | 6 | 6 | 9 | 7 | 8 | 7 | 7 | 6 | 7 | 6 | 10 | 8 |
| V | 5 | 8 | 7 | 7 | 6 | 7 | 7 | 5 | 6 | 5 | 7 | 7 | 8 | 7 | 7 | 7 | 6 | 5 | 8 | 7 |
| W | 9 | 11 | 9 | 9 | 7 | 9 | 12 | 10 | 10 | 7 | 9 | 11 | 11 | 11 | 10 | 9 | 10 | 8 | 6 | 9 |
| Y | 7 | 11 | 8 | 8 | 7 | 8 | 8 | 8 | 8 | 6 | 9 | 8 | 11 | 9 | 9 | 8 | 8 | 7 | 9 | 7 |
Distance LN |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 3 | 5 | 3 | 3 | 4 | 3 | 4 | 4 | 3 | 3 | 5 | 4 | 4 | 4 | 4 | 3 | 3 | 3 | 6 | 5 |
| C | 5 | 6 | 6 | 6 | 6 | 6 | 7 | 5 | 6 | 5 | 7 | 6 | 7 | 7 | 7 | 6 | 6 | 5 | 8 | 7 |
| D | 3 | 6 | 4 | 3 | 6 | 4 | 5 | 6 | 4 | 5 | 6 | 4 | 5 | 4 | 5 | 4 | 4 | 5 | 6 | 6 |
| E | 3 | 6 | 3 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 6 | 4 | 5 | 4 | 4 | 4 | 4 | 4 | 6 | 6 |
| F | 4 | 6 | 6 | 5 | 3 | 5 | 5 | 4 | 5 | 3 | 5 | 5 | 6 | 6 | 5 | 5 | 5 | 4 | 4 | 4 |
| G | 3 | 6 | 4 | 4 | 5 | 3 | 5 | 5 | 4 | 4 | 6 | 4 | 4 | 4 | 5 | 4 | 4 | 4 | 6 | 6 |
| H | 4 | 7 | 5 | 5 | 5 | 5 | 3 | 6 | 4 | 4 | 6 | 5 | 6 | 4 | 5 | 5 | 5 | 5 | 8 | 5 |
| I | 4 | 5 | 6 | 5 | 4 | 5 | 6 | 4 | 5 | 3 | 5 | 5 | 6 | 6 | 5 | 5 | 5 | 3 | 7 | 5 |
| K | 3 | 6 | 4 | 4 | 5 | 4 | 4 | 5 | 3 | 4 | 5 | 4 | 4 | 4 | 3 | 4 | 4 | 4 | 6 | 5 |
| L | 3 | 5 | 5 | 4 | 3 | 4 | 4 | 3 | 4 | 2 | 4 | 4 | 6 | 5 | 5 | 4 | 4 | 3 | 5 | 4 |
| M | 5 | 7 | 6 | 6 | 5 | 6 | 6 | 5 | 5 | 4 | 6 | 6 | 7 | 6 | 6 | 6 | 6 | 5 | 6 | 6 |
| N | 4 | 6 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 6 | 4 | 5 | 4 | 5 | 4 | 4 | 5 | 7 | 5 |
| P | 4 | 7 | 5 | 5 | 6 | 4 | 6 | 6 | 4 | 6 | 7 | 5 | 4 | 5 | 6 | 5 | 5 | 5 | 7 | 7 |
| Q | 4 | 7 | 4 | 4 | 6 | 4 | 4 | 6 | 4 | 5 | 6 | 4 | 5 | 5 | 5 | 4 | 5 | 5 | 7 | 6 |
| R | 4 | 7 | 5 | 4 | 5 | 5 | 5 | 5 | 3 | 5 | 6 | 5 | 6 | 5 | 4 | 5 | 5 | 5 | 7 | 6 |
| S | 3 | 6 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 6 | 4 | 5 | 4 | 5 | 4 | 4 | 4 | 6 | 5 |
| T | 3 | 6 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 6 | 4 | 5 | 5 | 5 | 4 | 4 | 4 | 6 | 5 |
| V | 3 | 5 | 5 | 4 | 4 | 4 | 5 | 3 | 4 | 3 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 3 | 5 | 5 |
| W | 6 | 8 | 6 | 6 | 4 | 6 | 8 | 7 | 6 | 5 | 6 | 7 | 7 | 7 | 7 | 6 | 6 | 5 | 4 | 6 |
| Y | 5 | 7 | 6 | 6 | 4 | 6 | 5 | 5 | 5 | 4 | 6 | 5 | 7 | 6 | 6 | 5 | 5 | 5 | 6 | 5 |
Distance Log10 |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
| C | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 2 | 2 | 3 | 3 |
| D | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| E | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| F | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 |
| G | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| H | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 3 | 2 |
| I | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 2 |
| K | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| L | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| M | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 |
| N | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 3 | 2 |
| P | 1 | 3 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 2 | 3 | 2 |
| Q | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| R | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 2 |
| S | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| T | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| V | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 2 |
| W | 2 | 3 | 2 | 2 | 1 | 2 | 3 | 2 | 2 | 1 | 2 | 3 | 3 | 2 | 2 | 2 | 2 | 2 | 1 | 2 |
| Y | 1 | 3 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
Observed Probability of Transition |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 2.40428% | 0.37141% | 1.23871% | 1.31016% | 0.70058% | 1.60956% | 0.63991% | 0.88402% | 1.77400% | 1.30903% | 0.28834% | 0.64586% | 0.62800% | 0.78904% | 0.74113% | 1.64897% | 1.11566% | 1.30534% | 0.12815% | 0.37793% |
| C | 0.37141% | 0.06747% | 0.09242% | 0.07570% | 0.11085% | 0.10660% | 0.05103% | 0.17493% | 0.08647% | 0.21406% | 0.03827% | 0.06662% | 0.03005% | 0.03855% | 0.03742% | 0.12588% | 0.11369% | 0.24354% | 0.01757% | 0.02891% |
| D | 1.23871% | 0.09242% | 0.93279% | 1.12955% | 0.13495% | 0.78536% | 0.34079% | 0.14799% | 0.86644% | 0.27331% | 0.08931% | 0.78167% | 0.39806% | 0.62035% | 0.38814% | 0.82335% | 0.71873% | 0.36914% | 0.08647% | 0.13864% |
| E | 1.31016% | 0.07570% | 1.12955% | 0.67705% | 0.17096% | 0.67507% | 0.33937% | 0.22625% | 1.06066% | 0.41961% | 0.11341% | 0.53557% | 0.34675% | 0.64303% | 0.45619% | 0.62602% | 0.56789% | 0.50382% | 0.07201% | 0.14232% |
| F | 0.70058% | 0.11085% | 0.13495% | 0.17096% | 2.36912% | 0.22455% | 0.15281% | 0.65295% | 0.20980% | 2.11055% | 0.33739% | 0.16529% | 0.07314% | 0.10263% | 0.17068% | 0.20158% | 0.23135% | 0.90699% | 0.41678% | 0.47915% |
| G | 1.60956% | 0.10660% | 0.78536% | 0.67507% | 0.22455% | 1.19703% | 0.37510% | 0.20895% | 0.83667% | 0.56903% | 0.12134% | 0.42556% | 0.43180% | 0.41734% | 0.36461% | 0.94838% | 0.54436% | 0.44740% | 0.07314% | 0.14459% |
| H | 0.63991% | 0.05103% | 0.34079% | 0.33937% | 0.15281% | 0.37510% | 1.45589% | 0.12191% | 0.59455% | 0.43010% | 0.06974% | 0.39551% | 0.10660% | 0.52820% | 0.27360% | 0.36602% | 0.25658% | 0.29288% | 0.01162% | 0.25772% |
| I | 0.88402% | 0.17493% | 0.14799% | 0.22625% | 0.65295% | 0.20895% | 0.12191% | 0.67110% | 0.38502% | 1.99090% | 0.31698% | 0.18060% | 0.06067% | 0.14431% | 0.17833% | 0.32520% | 0.40799% | 1.67279% | 0.05301% | 0.16699% |
| K | 1.77400% | 0.08647% | 0.86644% | 1.06066% | 0.20980% | 0.83667% | 0.59455% | 0.38502% | 1.45788% | 0.71731% | 0.18826% | 0.61212% | 0.50212% | 0.86673% | 1.22170% | 0.90926% | 0.74736% | 0.60305% | 0.06436% | 0.23901% |
| L | 1.30903% | 0.21406% | 0.27331% | 0.41961% | 2.11055% | 0.56903% | 0.43010% | 1.99090% | 0.71731% | 3.13520% | 0.77572% | 0.42613% | 0.14062% | 0.33654% | 0.32633% | 0.48709% | 0.68442% | 2.00281% | 0.33881% | 0.72156% |
| M | 0.28834% | 0.03827% | 0.08931% | 0.11341% | 0.33739% | 0.12134% | 0.06974% | 0.31698% | 0.18826% | 0.77572% | 0.08845% | 0.07853% | 0.04054% | 0.10036% | 0.11681% | 0.09923% | 0.12560% | 0.38502% | 0.08590% | 0.11199% |
| N | 0.64586% | 0.06662% | 0.78167% | 0.53557% | 0.16529% | 0.42556% | 0.39551% | 0.18060% | 0.61212% | 0.42613% | 0.07853% | 0.41791% | 0.16557% | 0.41564% | 0.29656% | 0.63481% | 0.47943% | 0.36773% | 0.02636% | 0.22511% |
| P | 0.62800% | 0.03005% | 0.39806% | 0.34675% | 0.07314% | 0.43180% | 0.10660% | 0.06067% | 0.50212% | 0.14062% | 0.04054% | 0.16557% | 0.95490% | 0.17975% | 0.09583% | 0.35752% | 0.21207% | 0.15168% | 0.02183% | 0.03402% |
| Q | 0.78904% | 0.03855% | 0.62035% | 0.64303% | 0.10263% | 0.41734% | 0.52820% | 0.14431% | 0.86673% | 0.33654% | 0.10036% | 0.41564% | 0.17975% | 0.33143% | 0.37680% | 0.42925% | 0.37028% | 0.32350% | 0.03288% | 0.10887% |
| R | 0.74113% | 0.03742% | 0.38814% | 0.45619% | 0.17068% | 0.36461% | 0.27360% | 0.17833% | 1.22170% | 0.32633% | 0.11681% | 0.29656% | 0.09583% | 0.37680% | 0.51402% | 0.34986% | 0.37878% | 0.30932% | 0.04139% | 0.11936% |
| S | 1.64897% | 0.12588% | 0.82335% | 0.62602% | 0.20158% | 0.94838% | 0.36602% | 0.32520% | 0.90926% | 0.48709% | 0.09923% | 0.63481% | 0.35752% | 0.42925% | 0.34986% | 0.67422% | 0.79386% | 0.44059% | 0.07371% | 0.18769% |
| T | 1.11566% | 0.11369% | 0.71873% | 0.56789% | 0.23135% | 0.54436% | 0.25658% | 0.40799% | 0.74736% | 0.68442% | 0.12560% | 0.47943% | 0.21207% | 0.37028% | 0.37878% | 0.79386% | 0.46129% | 0.65097% | 0.06124% | 0.19790% |
| V | 1.30534% | 0.24354% | 0.36914% | 0.50382% | 0.90699% | 0.44740% | 0.29288% | 1.67279% | 0.60305% | 2.00281% | 0.38502% | 0.36773% | 0.15168% | 0.32350% | 0.30932% | 0.44059% | 0.65097% | 1.56873% | 0.15962% | 0.29684% |
| W | 0.12815% | 0.01757% | 0.08647% | 0.07201% | 0.41678% | 0.07314% | 0.01162% | 0.05301% | 0.06436% | 0.33881% | 0.08590% | 0.02636% | 0.02183% | 0.03288% | 0.04139% | 0.07371% | 0.06124% | 0.15962% | 0.73886% | 0.07740% |
| Y | 0.37793% | 0.02891% | 0.13864% | 0.14232% | 0.47915% | 0.14459% | 0.25772% | 0.16699% | 0.23901% | 0.72156% | 0.11199% | 0.22511% | 0.03402% | 0.10887% | 0.11936% | 0.18769% | 0.19790% | 0.29684% | 0.07740% | 0.30081% |
Expected Probability of Transition |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1.24483% | 0.24088% | 1.25954% | 1.20146% | 1.37137% | 1.30579% | 0.95014% | 1.07578% | 1.71829% | 2.29218% | 0.40832% | 0.86587% | 0.65677% | 0.83534% | 0.81123% | 1.24702% | 1.06895% | 1.62567% | 0.37042% | 0.51967% |
| C | 0.24088% | 0.01165% | 0.12186% | 0.11624% | 0.13268% | 0.12634% | 0.09193% | 0.10408% | 0.16625% | 0.22178% | 0.03950% | 0.08377% | 0.06354% | 0.08082% | 0.07849% | 0.12065% | 0.10342% | 0.15729% | 0.03584% | 0.05028% |
| D | 1.25954% | 0.12186% | 0.31860% | 0.60783% | 0.69378% | 0.66061% | 0.48068% | 0.54425% | 0.86930% | 1.15963% | 0.20657% | 0.43805% | 0.33226% | 0.42260% | 0.41041% | 0.63087% | 0.54079% | 0.82244% | 0.18740% | 0.26290% |
| E | 1.20146% | 0.11624% | 0.60783% | 0.28990% | 0.66179% | 0.63015% | 0.45851% | 0.51915% | 0.82921% | 1.10616% | 0.19704% | 0.41785% | 0.31694% | 0.40312% | 0.39148% | 0.60178% | 0.51585% | 0.78451% | 0.17876% | 0.25078% |
| F | 1.37137% | 0.13268% | 0.69378% | 0.66179% | 0.37769% | 0.71926% | 0.52336% | 0.59257% | 0.94647% | 1.26259% | 0.22491% | 0.47694% | 0.36176% | 0.46012% | 0.44684% | 0.68688% | 0.58880% | 0.89545% | 0.20404% | 0.28624% |
| G | 1.30579% | 0.12634% | 0.66061% | 0.63015% | 0.71926% | 0.34243% | 0.49833% | 0.56423% | 0.90121% | 1.20221% | 0.21416% | 0.45413% | 0.34446% | 0.43812% | 0.42548% | 0.65404% | 0.56065% | 0.85264% | 0.19428% | 0.27256% |
| H | 0.95014% | 0.09193% | 0.48068% | 0.45851% | 0.52336% | 0.49833% | 0.18130% | 0.41055% | 0.65575% | 0.87477% | 0.15583% | 0.33044% | 0.25064% | 0.31879% | 0.30959% | 0.47590% | 0.40794% | 0.62040% | 0.14136% | 0.19832% |
| I | 1.07578% | 0.10408% | 0.54425% | 0.51915% | 0.59257% | 0.56423% | 0.41055% | 0.23242% | 0.74247% | 0.99045% | 0.17643% | 0.37414% | 0.28379% | 0.36095% | 0.35053% | 0.53883% | 0.46189% | 0.70245% | 0.16006% | 0.22455% |
| K | 1.71829% | 0.16625% | 0.86930% | 0.82921% | 0.94647% | 0.90121% | 0.65575% | 0.74247% | 0.59295% | 1.58199% | 0.28181% | 0.59759% | 0.45328% | 0.57652% | 0.55989% | 0.86065% | 0.73776% | 1.12198% | 0.25565% | 0.35866% |
| L | 2.29218% | 0.22178% | 1.15963% | 1.10616% | 1.26259% | 1.20221% | 0.87477% | 0.99045% | 1.58199% | 1.05518% | 0.37593% | 0.79718% | 0.60467% | 0.76908% | 0.74688% | 1.14810% | 0.98416% | 1.49672% | 0.34104% | 0.47845% |
| M | 0.40832% | 0.03950% | 0.20657% | 0.19704% | 0.22491% | 0.21416% | 0.15583% | 0.17643% | 0.28181% | 0.37593% | 0.03348% | 0.14200% | 0.10771% | 0.13700% | 0.13304% | 0.20452% | 0.17531% | 0.26662% | 0.06075% | 0.08523% |
| N | 0.86587% | 0.08377% | 0.43805% | 0.41785% | 0.47694% | 0.45413% | 0.33044% | 0.37414% | 0.59759% | 0.79718% | 0.14200% | 0.15056% | 0.22841% | 0.29051% | 0.28213% | 0.43369% | 0.37176% | 0.56538% | 0.12882% | 0.18073% |
| P | 0.65677% | 0.06354% | 0.33226% | 0.31694% | 0.36176% | 0.34446% | 0.25064% | 0.28379% | 0.45328% | 0.60467% | 0.10771% | 0.22841% | 0.08662% | 0.22036% | 0.21400% | 0.32896% | 0.28198% | 0.42885% | 0.09771% | 0.13708% |
| Q | 0.83534% | 0.08082% | 0.42260% | 0.40312% | 0.46012% | 0.43812% | 0.31879% | 0.36095% | 0.57652% | 0.76908% | 0.13700% | 0.29051% | 0.22036% | 0.14013% | 0.27218% | 0.41840% | 0.35865% | 0.54545% | 0.12428% | 0.17436% |
| R | 0.81123% | 0.07849% | 0.41041% | 0.39148% | 0.44684% | 0.42548% | 0.30959% | 0.35053% | 0.55989% | 0.74688% | 0.13304% | 0.28213% | 0.21400% | 0.27218% | 0.13216% | 0.40633% | 0.34831% | 0.52971% | 0.12070% | 0.16933% |
| S | 1.24702% | 0.12065% | 0.63087% | 0.60178% | 0.68688% | 0.65404% | 0.47590% | 0.53883% | 0.86065% | 1.14810% | 0.20452% | 0.43369% | 0.32896% | 0.41840% | 0.40633% | 0.31230% | 0.53541% | 0.81426% | 0.18553% | 0.26029% |
| T | 1.06895% | 0.10342% | 0.54079% | 0.51585% | 0.58880% | 0.56065% | 0.40794% | 0.46189% | 0.73776% | 0.98416% | 0.17531% | 0.37176% | 0.28198% | 0.35865% | 0.34831% | 0.53541% | 0.22948% | 0.69799% | 0.15904% | 0.22312% |
| V | 1.62567% | 0.15729% | 0.82244% | 0.78451% | 0.89545% | 0.85264% | 0.62040% | 0.70245% | 1.12198% | 1.49672% | 0.26662% | 0.56538% | 0.42885% | 0.54545% | 0.52971% | 0.81426% | 0.69799% | 0.53075% | 0.24187% | 0.33932% |
| W | 0.37042% | 0.03584% | 0.18740% | 0.17876% | 0.20404% | 0.19428% | 0.14136% | 0.16006% | 0.25565% | 0.34104% | 0.06075% | 0.12882% | 0.09771% | 0.12428% | 0.12070% | 0.18553% | 0.15904% | 0.24187% | 0.02755% | 0.07732% |
| Y | 0.51967% | 0.05028% | 0.26290% | 0.25078% | 0.28624% | 0.27256% | 0.19832% | 0.22455% | 0.35866% | 0.47845% | 0.08523% | 0.18073% | 0.13708% | 0.17436% | 0.16933% | 0.26029% | 0.22312% | 0.33932% | 0.07732% | 0.05423% |
Transition Count |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 8480 | 1310 | 4369 | 4621 | 2471 | 5677 | 2257 | 3118 | 6257 | 4617 | 1017 | 2278 | 2215 | 2783 | 2614 | 5816 | 3935 | 4604 | 452 | 1333 |
| C | 1310 | 238 | 326 | 267 | 391 | 376 | 180 | 617 | 305 | 755 | 135 | 235 | 106 | 136 | 132 | 444 | 401 | 859 | 62 | 102 |
| D | 4369 | 326 | 3290 | 3984 | 476 | 2770 | 1202 | 522 | 3056 | 964 | 315 | 2757 | 1404 | 2188 | 1369 | 2904 | 2535 | 1302 | 305 | 489 |
| E | 4621 | 267 | 3984 | 2388 | 603 | 2381 | 1197 | 798 | 3741 | 1480 | 400 | 1889 | 1223 | 2268 | 1609 | 2208 | 2003 | 1777 | 254 | 502 |
| F | 2471 | 391 | 476 | 603 | 8356 | 792 | 539 | 2303 | 740 | 7444 | 1190 | 583 | 258 | 362 | 602 | 711 | 816 | 3199 | 1470 | 1690 |
| G | 5677 | 376 | 2770 | 2381 | 792 | 4222 | 1323 | 737 | 2951 | 2007 | 428 | 1501 | 1523 | 1472 | 1286 | 3345 | 1920 | 1578 | 258 | 510 |
| H | 2257 | 180 | 1202 | 1197 | 539 | 1323 | 5135 | 430 | 2097 | 1517 | 246 | 1395 | 376 | 1863 | 965 | 1291 | 905 | 1033 | 41 | 909 |
| I | 3118 | 617 | 522 | 798 | 2303 | 737 | 430 | 2367 | 1358 | 7022 | 1118 | 637 | 214 | 509 | 629 | 1147 | 1439 | 5900 | 187 | 589 |
| K | 6257 | 305 | 3056 | 3741 | 740 | 2951 | 2097 | 1358 | 5142 | 2530 | 664 | 2159 | 1771 | 3057 | 4309 | 3207 | 2636 | 2127 | 227 | 843 |
| L | 4617 | 755 | 964 | 1480 | 7444 | 2007 | 1517 | 7022 | 2530 | 11058 | 2736 | 1503 | 496 | 1187 | 1151 | 1718 | 2414 | 7064 | 1195 | 2545 |
| M | 1017 | 135 | 315 | 400 | 1190 | 428 | 246 | 1118 | 664 | 2736 | 312 | 277 | 143 | 354 | 412 | 350 | 443 | 1358 | 303 | 395 |
| N | 2278 | 235 | 2757 | 1889 | 583 | 1501 | 1395 | 637 | 2159 | 1503 | 277 | 1474 | 584 | 1466 | 1046 | 2239 | 1691 | 1297 | 93 | 794 |
| P | 2215 | 106 | 1404 | 1223 | 258 | 1523 | 376 | 214 | 1771 | 496 | 143 | 584 | 3368 | 634 | 338 | 1261 | 748 | 535 | 77 | 120 |
| Q | 2783 | 136 | 2188 | 2268 | 362 | 1472 | 1863 | 509 | 3057 | 1187 | 354 | 1466 | 634 | 1169 | 1329 | 1514 | 1306 | 1141 | 116 | 384 |
| R | 2614 | 132 | 1369 | 1609 | 602 | 1286 | 965 | 629 | 4309 | 1151 | 412 | 1046 | 338 | 1329 | 1813 | 1234 | 1336 | 1091 | 146 | 421 |
| S | 5816 | 444 | 2904 | 2208 | 711 | 3345 | 1291 | 1147 | 3207 | 1718 | 350 | 2239 | 1261 | 1514 | 1234 | 2378 | 2800 | 1554 | 260 | 662 |
| T | 3935 | 401 | 2535 | 2003 | 816 | 1920 | 905 | 1439 | 2636 | 2414 | 443 | 1691 | 748 | 1306 | 1336 | 2800 | 1627 | 2296 | 216 | 698 |
| V | 4604 | 859 | 1302 | 1777 | 3199 | 1578 | 1033 | 5900 | 2127 | 7064 | 1358 | 1297 | 535 | 1141 | 1091 | 1554 | 2296 | 5533 | 563 | 1047 |
| W | 452 | 62 | 305 | 254 | 1470 | 258 | 41 | 187 | 227 | 1195 | 303 | 93 | 77 | 116 | 146 | 260 | 216 | 563 | 2606 | 273 |
| Y | 1333 | 102 | 489 | 502 | 1690 | 510 | 909 | 589 | 843 | 2545 | 395 | 794 | 120 | 384 | 421 | 662 | 698 | 1047 | 273 | 1061 |
Number of Amino Acids in Alignment |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1111 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| C | - | 108 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| D | - | - | 602 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| E | - | - | - | 552 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| F | - | - | - | - | 600 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| G | - | - | - | - | - | 613 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| H | - | - | - | - | - | - | 427 | - | - | - | - | - | - | - | - | - | - | - | - | - |
| I | - | - | - | - | - | - | - | 475 | - | - | - | - | - | - | - | - | - | - | - | - |
| K | - | - | - | - | - | - | - | - | 773 | - | - | - | - | - | - | - | - | - | - | - |
| L | - | - | - | - | - | - | - | - | - | 1009 | - | - | - | - | - | - | - | - | - | - |
| M | - | - | - | - | - | - | - | - | - | - | 185 | - | - | - | - | - | - | - | - | - |
| N | - | - | - | - | - | - | - | - | - | - | - | 404 | - | - | - | - | - | - | - | - |
| P | - | - | - | - | - | - | - | - | - | - | - | - | 304 | - | - | - | - | - | - | - |
| Q | - | - | - | - | - | - | - | - | - | - | - | - | - | 372 | - | - | - | - | - | - |
| R | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 368 | - | - | - | - | - |
| S | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 573 | - | - | - | - |
| T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 487 | - | - | - |
| V | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 722 | - | - |
| W | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 163 | - |
| Y | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 228 |
Percentage of Amino Acids in Alignment |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 11.0% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| C | - | 1.07% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| D | - | - | 5.97% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| E | - | - | - | 5.47% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| F | - | - | - | - | 5.95% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| G | - | - | - | - | - | 6.08% | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| H | - | - | - | - | - | - | 4.23% | - | - | - | - | - | - | - | - | - | - | - | - | - |
| I | - | - | - | - | - | - | - | 4.71% | - | - | - | - | - | - | - | - | - | - | - | - |
| K | - | - | - | - | - | - | - | - | 7.67% | - | - | - | - | - | - | - | - | - | - | - |
| L | - | - | - | - | - | - | - | - | - | 10.0% | - | - | - | - | - | - | - | - | - | - |
| M | - | - | - | - | - | - | - | - | - | - | 1.83% | - | - | - | - | - | - | - | - | - |
| N | - | - | - | - | - | - | - | - | - | - | - | 4.00% | - | - | - | - | - | - | - | - |
| P | - | - | - | - | - | - | - | - | - | - | - | - | 3.01% | - | - | - | - | - | - | - |
| Q | - | - | - | - | - | - | - | - | - | - | - | - | - | 3.69% | - | - | - | - | - | - |
| R | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 3.65% | - | - | - | - | - |
| S | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 5.68% | - | - | - | - |
| T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4.83% | - | - | - |
| V | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.16% | - | - |
| W | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1.61% | - |
| Y | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 2.26% |