Accession number: PF00001 |
Blosum Log2 No Clustering |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 3 | 0 | -2 | -1 | -1 | 1 | -1 | -1 | -1 | 0 | -1 | -2 | -1 | -1 | -1 | 1 | 0 | 0 | -2 | -2 |
| C | 0 | 6 | -3 | -2 | -1 | -1 | -2 | -1 | -3 | -1 | 0 | -2 | -3 | -3 | -3 | 0 | 0 | -1 | -2 | -3 |
| D | -2 | -3 | 8 | 3 | -2 | -1 | 1 | -3 | 0 | -3 | -2 | 2 | -1 | 1 | 0 | -1 | -1 | -3 | -2 | -1 |
| E | -1 | -2 | 3 | 4 | -2 | 1 | 1 | -3 | 2 | -2 | -1 | 0 | 1 | 2 | 1 | 1 | 0 | -2 | -2 | -1 |
| F | -1 | -1 | -2 | -2 | 3 | -1 | 0 | 0 | -2 | 1 | 0 | -2 | -2 | -1 | -2 | -1 | 0 | 0 | 0 | 1 |
| G | 1 | -1 | -1 | 1 | -1 | 4 | -1 | -1 | -1 | -1 | -1 | -1 | 0 | 0 | -1 | 1 | 0 | -1 | -1 | -2 |
| H | -1 | -2 | 1 | 1 | 0 | -1 | 3 | -2 | 2 | -1 | -1 | 2 | -1 | 2 | 2 | 0 | 0 | -1 | -2 | 1 |
| I | -1 | -1 | -3 | -3 | 0 | -1 | -2 | 3 | -2 | 1 | 1 | -3 | -3 | -2 | -3 | -1 | -1 | 1 | -2 | -1 |
| K | -1 | -3 | 0 | 2 | -2 | -1 | 2 | -2 | 4 | -2 | -1 | 0 | -1 | 3 | 4 | 0 | 0 | -2 | 0 | -1 |
| L | 0 | -1 | -3 | -2 | 1 | -1 | -1 | 1 | -2 | 2 | 1 | -2 | -2 | -1 | -2 | -1 | -1 | 1 | -2 | -1 |
| M | -1 | 0 | -2 | -1 | 0 | -1 | -1 | 1 | -1 | 1 | 2 | -2 | -1 | 0 | -1 | -1 | 0 | 0 | -1 | -1 |
| N | -2 | -2 | 2 | 0 | -2 | -1 | 2 | -3 | 0 | -2 | -2 | 6 | -2 | 0 | 0 | 1 | 0 | -2 | -2 | -1 |
| P | -1 | -3 | -1 | 1 | -2 | 0 | -1 | -3 | -1 | -2 | -1 | -2 | 7 | 0 | -1 | -1 | -1 | -2 | -3 | -3 |
| Q | -1 | -3 | 1 | 2 | -1 | 0 | 2 | -2 | 3 | -1 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | -1 | 0 | -1 |
| R | -1 | -3 | 0 | 1 | -2 | -1 | 2 | -3 | 4 | -2 | -1 | 0 | -1 | 3 | 5 | 0 | 0 | -2 | -1 | -2 |
| S | 1 | 0 | -1 | 1 | -1 | 1 | 0 | -1 | 0 | -1 | -1 | 1 | -1 | 0 | 0 | 3 | 1 | -1 | -2 | -1 |
| T | 0 | 0 | -1 | 0 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | -1 | 0 | 0 | 1 | 2 | 0 | -2 | -1 |
| V | 0 | -1 | -3 | -2 | 0 | -1 | -1 | 1 | -2 | 1 | 0 | -2 | -2 | -1 | -2 | -1 | 0 | 2 | -2 | -1 |
| W | -2 | -2 | -2 | -2 | 0 | -1 | -2 | -2 | 0 | -2 | -1 | -2 | -3 | 0 | -1 | -2 | -2 | -2 | 8 | 0 |
| Y | -2 | -3 | -1 | -1 | 1 | -2 | 1 | -1 | -1 | -1 | -1 | -1 | -3 | -1 | -2 | -1 | -1 | -1 | 0 | 6 |
Blosum LN No Clustering |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 2 | 0 | -2 | -1 | -1 | 0 | -1 | 0 | -1 | 0 | 0 | -1 | -1 | -1 | -1 | 1 | 0 | 0 | -2 | -1 |
| C | 0 | 4 | -2 | -2 | 0 | -1 | -1 | -1 | -2 | -1 | 0 | -2 | -2 | -2 | -2 | 0 | 0 | -1 | -1 | -2 |
| D | -2 | -2 | 5 | 2 | -1 | -1 | 1 | -2 | 0 | -2 | -1 | 1 | 0 | 1 | 0 | -1 | -1 | -2 | -1 | -1 |
| E | -1 | -2 | 2 | 3 | -1 | 1 | 1 | -2 | 1 | -1 | -1 | 0 | 1 | 1 | 1 | 1 | 0 | -1 | -2 | -1 |
| F | -1 | 0 | -1 | -1 | 2 | 0 | 0 | 0 | -1 | 0 | 0 | -1 | -1 | -1 | -2 | -1 | 0 | 0 | 0 | 1 |
| G | 0 | -1 | -1 | 1 | 0 | 3 | -1 | -1 | -1 | 0 | 0 | -1 | 0 | 0 | 0 | 1 | 0 | 0 | -1 | -1 |
| H | -1 | -1 | 1 | 1 | 0 | -1 | 2 | -1 | 1 | -1 | -1 | 2 | 0 | 1 | 1 | 0 | 0 | -1 | -1 | 0 |
| I | 0 | -1 | -2 | -2 | 0 | -1 | -1 | 2 | -2 | 1 | 1 | -2 | -2 | -1 | -2 | -1 | 0 | 1 | -2 | -1 |
| K | -1 | -2 | 0 | 1 | -1 | -1 | 1 | -2 | 3 | -1 | -1 | 0 | -1 | 2 | 2 | 0 | 0 | -1 | 0 | -1 |
| L | 0 | -1 | -2 | -1 | 0 | 0 | -1 | 1 | -1 | 1 | 1 | -2 | -1 | -1 | -1 | -1 | 0 | 0 | -1 | -1 |
| M | 0 | 0 | -1 | -1 | 0 | 0 | -1 | 1 | -1 | 1 | 2 | -1 | -1 | 0 | -1 | -1 | 0 | 0 | -1 | -1 |
| N | -1 | -2 | 1 | 0 | -1 | -1 | 2 | -2 | 0 | -2 | -1 | 4 | -1 | 0 | 0 | 0 | 0 | -2 | -2 | -1 |
| P | -1 | -2 | 0 | 1 | -1 | 0 | 0 | -2 | -1 | -1 | -1 | -1 | 5 | 0 | -1 | -1 | -1 | -1 | -2 | -2 |
| Q | -1 | -2 | 1 | 1 | -1 | 0 | 1 | -1 | 2 | -1 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | -1 | 0 | 0 |
| R | -1 | -2 | 0 | 1 | -2 | 0 | 1 | -2 | 2 | -1 | -1 | 0 | -1 | 2 | 3 | 0 | 0 | -1 | -1 | -1 |
| S | 1 | 0 | -1 | 1 | -1 | 1 | 0 | -1 | 0 | -1 | -1 | 0 | -1 | 0 | 0 | 2 | 0 | -1 | -1 | -1 |
| T | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 1 | 0 | -2 | 0 |
| V | 0 | -1 | -2 | -1 | 0 | 0 | -1 | 1 | -1 | 0 | 0 | -2 | -1 | -1 | -1 | -1 | 0 | 1 | -2 | -1 |
| W | -2 | -1 | -1 | -2 | 0 | -1 | -1 | -2 | 0 | -1 | -1 | -2 | -2 | 0 | -1 | -1 | -2 | -2 | 6 | 0 |
| Y | -1 | -2 | -1 | -1 | 1 | -1 | 0 | -1 | -1 | -1 | -1 | -1 | -2 | 0 | -1 | -1 | 0 | -1 | 0 | 4 |
Blosum Log10 No Clustering |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | -1 |
| C | 0 | 2 | -1 | -1 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | -1 | -1 | -1 | -1 | 0 | 0 | 0 | -1 | -1 |
| D | -1 | -1 | 2 | 1 | 0 | 0 | 0 | -1 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | -1 | 0 |
| E | 0 | -1 | 1 | 1 | 0 | 0 | 0 | -1 | 1 | -1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | -1 | -1 | 0 |
| F | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 |
| G | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| H | 0 | -1 | 0 | 0 | 0 | 0 | 1 | -1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | -1 | 0 |
| I | 0 | 0 | -1 | -1 | 0 | 0 | -1 | 1 | -1 | 0 | 0 | -1 | -1 | -1 | -1 | 0 | 0 | 0 | -1 | 0 |
| K | 0 | -1 | 0 | 1 | -1 | 0 | 1 | -1 | 1 | -1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | -1 | 0 | 0 |
| L | 0 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | -1 | 1 | 0 | -1 | -1 | 0 | -1 | 0 | 0 | 0 | -1 | 0 |
| M | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| N | -1 | -1 | 0 | 0 | 0 | 0 | 1 | -1 | 0 | -1 | -1 | 2 | -1 | 0 | 0 | 0 | 0 | -1 | -1 | 0 |
| P | 0 | -1 | 0 | 0 | -1 | 0 | 0 | -1 | 0 | -1 | 0 | -1 | 2 | 0 | 0 | 0 | 0 | -1 | -1 | -1 |
| Q | 0 | -1 | 0 | 1 | 0 | 0 | 1 | -1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| R | 0 | -1 | 0 | 0 | -1 | 0 | 1 | -1 | 1 | -1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | -1 | 0 | -1 |
| S | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| T | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | -1 | 0 |
| V | 0 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | -1 | 0 | 0 | -1 | -1 | 0 | -1 | 0 | 0 | 1 | -1 | 0 |
| W | -1 | -1 | -1 | -1 | 0 | 0 | -1 | -1 | 0 | -1 | 0 | -1 | -1 | 0 | 0 | 0 | -1 | -1 | 3 | 0 |
| Y | -1 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 2 |
Distance Log2 |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 5 | 7 | 8 | 8 | 6 | 6 | 8 | 6 | 7 | 5 | 7 | 7 | 7 | 8 | 7 | 5 | 6 | 5 | 8 | 7 |
| C | 7 | 5 | 10 | 10 | 7 | 8 | 10 | 7 | 9 | 6 | 8 | 9 | 9 | 10 | 9 | 7 | 7 | 7 | 9 | 9 |
| D | 8 | 10 | 6 | 7 | 8 | 8 | 9 | 9 | 8 | 8 | 9 | 7 | 8 | 9 | 8 | 8 | 8 | 8 | 10 | 8 |
| E | 8 | 10 | 7 | 8 | 8 | 8 | 9 | 8 | 7 | 7 | 9 | 8 | 8 | 8 | 8 | 7 | 8 | 8 | 10 | 9 |
| F | 6 | 7 | 8 | 8 | 5 | 7 | 8 | 5 | 8 | 5 | 7 | 7 | 8 | 8 | 8 | 6 | 6 | 5 | 7 | 6 |
| G | 6 | 8 | 8 | 8 | 7 | 6 | 9 | 7 | 8 | 6 | 8 | 8 | 7 | 8 | 7 | 6 | 7 | 6 | 9 | 8 |
| H | 8 | 10 | 9 | 9 | 8 | 9 | 9 | 8 | 8 | 7 | 9 | 7 | 9 | 8 | 7 | 7 | 8 | 8 | 10 | 8 |
| I | 6 | 7 | 9 | 8 | 5 | 7 | 8 | 5 | 8 | 4 | 6 | 8 | 8 | 8 | 7 | 6 | 6 | 4 | 8 | 7 |
| K | 7 | 9 | 8 | 7 | 8 | 8 | 8 | 8 | 7 | 7 | 8 | 8 | 8 | 7 | 6 | 7 | 7 | 7 | 8 | 8 |
| L | 5 | 6 | 8 | 7 | 5 | 6 | 7 | 4 | 7 | 4 | 5 | 7 | 7 | 7 | 6 | 5 | 5 | 4 | 7 | 6 |
| M | 7 | 8 | 9 | 9 | 7 | 8 | 9 | 6 | 8 | 5 | 8 | 9 | 8 | 9 | 8 | 7 | 7 | 6 | 9 | 8 |
| N | 7 | 9 | 7 | 8 | 7 | 8 | 7 | 8 | 8 | 7 | 9 | 5 | 8 | 8 | 7 | 6 | 7 | 7 | 9 | 8 |
| P | 7 | 9 | 8 | 8 | 8 | 7 | 9 | 8 | 8 | 7 | 8 | 8 | 5 | 8 | 8 | 7 | 7 | 7 | 10 | 9 |
| Q | 8 | 10 | 9 | 8 | 8 | 8 | 8 | 8 | 7 | 7 | 9 | 8 | 8 | 9 | 7 | 7 | 8 | 8 | 9 | 8 |
| R | 7 | 9 | 8 | 8 | 8 | 7 | 7 | 7 | 6 | 6 | 8 | 7 | 8 | 7 | 6 | 6 | 7 | 7 | 9 | 8 |
| S | 5 | 7 | 8 | 7 | 6 | 6 | 7 | 6 | 7 | 5 | 7 | 6 | 7 | 7 | 6 | 5 | 6 | 6 | 8 | 7 |
| T | 6 | 7 | 8 | 8 | 6 | 7 | 8 | 6 | 7 | 5 | 7 | 7 | 7 | 8 | 7 | 6 | 6 | 5 | 9 | 7 |
| V | 5 | 7 | 8 | 8 | 5 | 6 | 8 | 4 | 7 | 4 | 6 | 7 | 7 | 8 | 7 | 6 | 5 | 5 | 8 | 7 |
| W | 8 | 9 | 10 | 10 | 7 | 9 | 10 | 8 | 8 | 7 | 9 | 9 | 10 | 9 | 9 | 8 | 9 | 8 | 6 | 8 |
| Y | 7 | 9 | 8 | 9 | 6 | 8 | 8 | 7 | 8 | 6 | 8 | 8 | 9 | 8 | 8 | 7 | 7 | 7 | 8 | 5 |
Distance LN |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 3 | 4 | 5 | 5 | 4 | 4 | 5 | 4 | 5 | 3 | 4 | 5 | 5 | 5 | 4 | 3 | 4 | 3 | 5 | 5 |
| C | 4 | 3 | 6 | 6 | 5 | 5 | 6 | 4 | 6 | 4 | 5 | 6 | 6 | 6 | 6 | 4 | 4 | 4 | 6 | 6 |
| D | 5 | 6 | 4 | 5 | 5 | 6 | 6 | 6 | 5 | 5 | 6 | 5 | 6 | 6 | 5 | 5 | 5 | 5 | 7 | 6 |
| E | 5 | 6 | 5 | 5 | 5 | 5 | 6 | 6 | 5 | 5 | 6 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 7 | 6 |
| F | 4 | 5 | 5 | 5 | 3 | 4 | 5 | 3 | 5 | 3 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 3 | 5 | 4 |
| G | 4 | 5 | 6 | 5 | 4 | 4 | 6 | 4 | 5 | 4 | 5 | 5 | 5 | 6 | 5 | 4 | 4 | 4 | 6 | 5 |
| H | 5 | 6 | 6 | 6 | 5 | 6 | 6 | 5 | 5 | 5 | 6 | 5 | 6 | 6 | 5 | 5 | 5 | 5 | 7 | 5 |
| I | 4 | 4 | 6 | 6 | 3 | 4 | 5 | 3 | 5 | 3 | 4 | 5 | 5 | 5 | 5 | 4 | 4 | 3 | 5 | 4 |
| K | 5 | 6 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 6 | 5 | 5 | 5 | 4 | 4 | 5 | 5 | 6 | 5 |
| L | 3 | 4 | 5 | 5 | 3 | 4 | 5 | 3 | 4 | 2 | 3 | 4 | 4 | 5 | 4 | 3 | 3 | 2 | 5 | 4 |
| M | 4 | 5 | 6 | 6 | 5 | 5 | 6 | 4 | 6 | 3 | 5 | 6 | 5 | 6 | 5 | 5 | 4 | 4 | 6 | 5 |
| N | 5 | 6 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 6 | 3 | 6 | 5 | 5 | 4 | 4 | 5 | 6 | 5 |
| P | 5 | 6 | 6 | 5 | 5 | 5 | 6 | 5 | 5 | 4 | 5 | 6 | 3 | 6 | 5 | 5 | 5 | 5 | 6 | 6 |
| Q | 5 | 6 | 6 | 5 | 5 | 6 | 6 | 5 | 5 | 5 | 6 | 5 | 6 | 6 | 4 | 5 | 5 | 5 | 6 | 6 |
| R | 4 | 6 | 5 | 5 | 5 | 5 | 5 | 5 | 4 | 4 | 5 | 5 | 5 | 4 | 4 | 4 | 4 | 5 | 6 | 5 |
| S | 3 | 4 | 5 | 5 | 4 | 4 | 5 | 4 | 4 | 3 | 5 | 4 | 5 | 5 | 4 | 3 | 4 | 4 | 5 | 4 |
| T | 4 | 4 | 5 | 5 | 4 | 4 | 5 | 4 | 5 | 3 | 4 | 4 | 5 | 5 | 4 | 4 | 4 | 3 | 6 | 4 |
| V | 3 | 4 | 5 | 5 | 3 | 4 | 5 | 3 | 5 | 2 | 4 | 5 | 5 | 5 | 5 | 4 | 3 | 3 | 5 | 4 |
| W | 5 | 6 | 7 | 7 | 5 | 6 | 7 | 5 | 6 | 5 | 6 | 6 | 6 | 6 | 6 | 5 | 6 | 5 | 4 | 5 |
| Y | 5 | 6 | 6 | 6 | 4 | 5 | 5 | 4 | 5 | 4 | 5 | 5 | 6 | 6 | 5 | 4 | 4 | 4 | 5 | 3 |
Distance Log10 |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 |
| C | 1 | 1 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 2 |
| D | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
| E | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 |
| F | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 1 |
| G | 1 | 2 | 2 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 2 |
| H | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 2 |
| I | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 1 |
| K | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| L | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 1 |
| M | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 2 |
| N | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 2 | 2 |
| P | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 2 |
| Q | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 2 |
| R | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 2 |
| S | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 |
| T | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 |
| V | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 1 |
| W | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 |
| Y | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 1 |
Observed Probability of Transition |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1.55963% | 0.53932% | 0.15767% | 0.24153% | 0.73694% | 0.76768% | 0.19929% | 1.03055% | 0.38750% | 1.76101% | 0.41113% | 0.32434% | 0.40674% | 0.22940% | 0.45337% | 1.56674% | 1.09914% | 1.61379% | 0.15893% | 0.38394% |
| C | 0.53932% | 1.18823% | 0.05750% | 0.06838% | 0.37976% | 0.22459% | 0.06859% | 0.46174% | 0.08574% | 0.75932% | 0.20661% | 0.12463% | 0.11355% | 0.05709% | 0.10916% | 0.48955% | 0.46299% | 0.51214% | 0.08636% | 0.13551% |
| D | 0.15767% | 0.05750% | 0.75534% | 0.30908% | 0.17817% | 0.14283% | 0.11794% | 0.11961% | 0.18298% | 0.22815% | 0.07235% | 0.30573% | 0.14534% | 0.12442% | 0.18737% | 0.23714% | 0.19281% | 0.15056% | 0.05228% | 0.14764% |
| E | 0.24153% | 0.06838% | 0.30908% | 0.17294% | 0.15935% | 0.21706% | 0.12108% | 0.14366% | 0.27917% | 0.30531% | 0.08845% | 0.18590% | 0.23986% | 0.15726% | 0.27395% | 0.38708% | 0.22794% | 0.20807% | 0.04161% | 0.12798% |
| F | 0.73694% | 0.37976% | 0.17817% | 0.15935% | 1.24720% | 0.43100% | 0.23860% | 1.12486% | 0.22543% | 2.12488% | 0.40381% | 0.28607% | 0.25011% | 0.18340% | 0.24550% | 0.59662% | 0.70306% | 1.24281% | 0.31556% | 0.92055% |
| G | 0.76768% | 0.22459% | 0.14283% | 0.21706% | 0.43100% | 0.67692% | 0.11313% | 0.45149% | 0.20724% | 0.85844% | 0.20326% | 0.20870% | 0.28733% | 0.14492% | 0.29130% | 0.75074% | 0.45630% | 0.61711% | 0.12672% | 0.21142% |
| H | 0.19929% | 0.06859% | 0.11794% | 0.12108% | 0.23860% | 0.11313% | 0.11543% | 0.16771% | 0.25178% | 0.31870% | 0.08344% | 0.31263% | 0.12150% | 0.14868% | 0.32434% | 0.28210% | 0.19929% | 0.23128% | 0.04600% | 0.21393% |
| I | 1.03055% | 0.46174% | 0.11961% | 0.14366% | 1.12486% | 0.45149% | 0.16771% | 1.78673% | 0.24718% | 2.96681% | 0.75053% | 0.24279% | 0.26495% | 0.17921% | 0.28524% | 0.71519% | 0.80930% | 2.56216% | 0.17043% | 0.47157% |
| K | 0.38750% | 0.08574% | 0.18298% | 0.27917% | 0.22543% | 0.20724% | 0.25178% | 0.24718% | 0.52698% | 0.48077% | 0.14366% | 0.27311% | 0.18381% | 0.32853% | 1.01005% | 0.46466% | 0.36199% | 0.34379% | 0.14303% | 0.20243% |
| L | 1.76101% | 0.75932% | 0.22815% | 0.30531% | 2.12488% | 0.85844% | 0.31870% | 2.96681% | 0.48077% | 3.47205% | 1.15309% | 0.44543% | 0.52573% | 0.32832% | 0.56044% | 1.18363% | 1.32855% | 3.25080% | 0.30866% | 0.88312% |
| M | 0.41113% | 0.20661% | 0.07235% | 0.08845% | 0.40381% | 0.20326% | 0.08344% | 0.75053% | 0.14366% | 1.15309% | 0.23087% | 0.12923% | 0.18340% | 0.10707% | 0.19343% | 0.32476% | 0.41197% | 0.70829% | 0.09933% | 0.21100% |
| N | 0.32434% | 0.12463% | 0.30573% | 0.18590% | 0.28607% | 0.20870% | 0.31263% | 0.24279% | 0.27311% | 0.44543% | 0.12923% | 1.18070% | 0.14534% | 0.16353% | 0.31995% | 0.66354% | 0.44835% | 0.30573% | 0.07821% | 0.26684% |
| P | 0.40674% | 0.11355% | 0.14534% | 0.23986% | 0.25011% | 0.28733% | 0.12150% | 0.26495% | 0.18381% | 0.52573% | 0.18340% | 0.14534% | 1.68552% | 0.14492% | 0.21602% | 0.37934% | 0.33124% | 0.39147% | 0.05562% | 0.13362% |
| Q | 0.22940% | 0.05709% | 0.12442% | 0.15726% | 0.18340% | 0.14492% | 0.14868% | 0.17921% | 0.32853% | 0.32832% | 0.10707% | 0.16353% | 0.14492% | 0.09598% | 0.42075% | 0.31138% | 0.24697% | 0.24195% | 0.10142% | 0.14303% |
| R | 0.45337% | 0.10916% | 0.18737% | 0.27395% | 0.24550% | 0.29130% | 0.32434% | 0.28524% | 1.01005% | 0.56044% | 0.19343% | 0.31995% | 0.21602% | 0.42075% | 1.03410% | 0.57529% | 0.45400% | 0.40841% | 0.13216% | 0.22208% |
| S | 1.56674% | 0.48955% | 0.23714% | 0.38708% | 0.59662% | 0.75074% | 0.28210% | 0.71519% | 0.46466% | 1.18363% | 0.32476% | 0.66354% | 0.37934% | 0.31138% | 0.57529% | 1.14326% | 1.01654% | 0.96467% | 0.18402% | 0.43685% |
| T | 1.09914% | 0.46299% | 0.19281% | 0.22794% | 0.70306% | 0.45630% | 0.19929% | 0.80930% | 0.36199% | 1.32855% | 0.41197% | 0.44835% | 0.33124% | 0.24697% | 0.45400% | 1.01654% | 0.71122% | 1.13030% | 0.12254% | 0.44082% |
| V | 1.61379% | 0.51214% | 0.15056% | 0.20807% | 1.24281% | 0.61711% | 0.23128% | 2.56216% | 0.34379% | 3.25080% | 0.70829% | 0.30573% | 0.39147% | 0.24195% | 0.40841% | 0.96467% | 1.13030% | 1.76540% | 0.19302% | 0.53577% |
| W | 0.15893% | 0.08636% | 0.05228% | 0.04161% | 0.31556% | 0.12672% | 0.04600% | 0.17043% | 0.14303% | 0.30866% | 0.09933% | 0.07821% | 0.05562% | 0.10142% | 0.13216% | 0.18402% | 0.12254% | 0.19302% | 0.94795% | 0.20075% |
| Y | 0.38394% | 0.13551% | 0.14764% | 0.12798% | 0.92055% | 0.21142% | 0.21393% | 0.47157% | 0.20243% | 0.88312% | 0.21100% | 0.26684% | 0.13362% | 0.14303% | 0.22208% | 0.43685% | 0.44082% | 0.53577% | 0.20075% | 1.38668% |
Expected Probability of Transition |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 0.60749% | 0.57046% | 0.36011% | 0.32179% | 1.03202% | 0.62861% | 0.29547% | 1.30463% | 0.53443% | 2.08224% | 0.49466% | 0.59169% | 0.61503% | 0.30820% | 0.68207% | 1.07688% | 0.92490% | 1.49204% | 0.35172% | 0.70633% |
| C | 0.57046% | 0.13392% | 0.16908% | 0.15109% | 0.48455% | 0.29514% | 0.13873% | 0.61255% | 0.25093% | 0.97765% | 0.23225% | 0.27781% | 0.28877% | 0.14470% | 0.32025% | 0.50561% | 0.43426% | 0.70054% | 0.16514% | 0.33163% |
| D | 0.36011% | 0.16908% | 0.05336% | 0.09538% | 0.30588% | 0.18632% | 0.08757% | 0.38668% | 0.15840% | 0.61716% | 0.14661% | 0.17537% | 0.18229% | 0.09135% | 0.20216% | 0.31918% | 0.27413% | 0.44223% | 0.10425% | 0.20935% |
| E | 0.32179% | 0.15109% | 0.09538% | 0.04261% | 0.27334% | 0.16649% | 0.07825% | 0.34554% | 0.14155% | 0.55149% | 0.13101% | 0.15671% | 0.16289% | 0.08163% | 0.18065% | 0.28522% | 0.24496% | 0.39517% | 0.09315% | 0.18707% |
| F | 1.03202% | 0.48455% | 0.30588% | 0.27334% | 0.43830% | 0.53395% | 0.25098% | 1.10817% | 0.45396% | 1.76868% | 0.42017% | 0.50259% | 0.52242% | 0.26179% | 0.57936% | 0.91471% | 0.78562% | 1.26736% | 0.29875% | 0.59996% |
| G | 0.62861% | 0.29514% | 0.18632% | 0.16649% | 0.53395% | 0.16261% | 0.15287% | 0.67499% | 0.27651% | 1.07732% | 0.25593% | 0.30613% | 0.31821% | 0.15946% | 0.35289% | 0.55716% | 0.47853% | 0.77196% | 0.18197% | 0.36544% |
| H | 0.29547% | 0.13873% | 0.08757% | 0.07825% | 0.25098% | 0.15287% | 0.03592% | 0.31727% | 0.12997% | 0.50638% | 0.12029% | 0.14389% | 0.14957% | 0.07495% | 0.16587% | 0.26188% | 0.22493% | 0.36285% | 0.08553% | 0.17177% |
| I | 1.30463% | 0.61255% | 0.38668% | 0.34554% | 1.10817% | 0.67499% | 0.31727% | 0.70044% | 0.57387% | 2.23587% | 0.53116% | 0.63535% | 0.66041% | 0.33094% | 0.73240% | 1.15633% | 0.99314% | 1.60213% | 0.37767% | 0.75844% |
| K | 0.53443% | 0.25093% | 0.15840% | 0.14155% | 0.45396% | 0.27651% | 0.12997% | 0.57387% | 0.11754% | 0.91592% | 0.21759% | 0.26027% | 0.27053% | 0.13557% | 0.30002% | 0.47369% | 0.40684% | 0.65630% | 0.15471% | 0.31069% |
| L | 2.08224% | 0.97765% | 0.61716% | 0.55149% | 1.76868% | 1.07732% | 0.50638% | 2.23587% | 0.91592% | 1.78427% | 0.84776% | 1.01405% | 1.05405% | 0.52820% | 1.16894% | 1.84555% | 1.58510% | 2.55706% | 0.60278% | 1.21051% |
| M | 0.49466% | 0.23225% | 0.14661% | 0.13101% | 0.42017% | 0.25593% | 0.12029% | 0.53116% | 0.21759% | 0.84776% | 0.10070% | 0.24090% | 0.25040% | 0.12548% | 0.27770% | 0.43844% | 0.37656% | 0.60746% | 0.14320% | 0.28757% |
| N | 0.59169% | 0.27781% | 0.17537% | 0.15671% | 0.50259% | 0.30613% | 0.14389% | 0.63535% | 0.26027% | 1.01405% | 0.24090% | 0.14407% | 0.29952% | 0.15009% | 0.33217% | 0.52444% | 0.45043% | 0.72662% | 0.17129% | 0.34398% |
| P | 0.61503% | 0.28877% | 0.18229% | 0.16289% | 0.52242% | 0.31821% | 0.14957% | 0.66041% | 0.27053% | 1.05405% | 0.25040% | 0.29952% | 0.15567% | 0.15601% | 0.34527% | 0.54512% | 0.46819% | 0.75528% | 0.17804% | 0.35755% |
| Q | 0.30820% | 0.14470% | 0.09135% | 0.08163% | 0.26179% | 0.15946% | 0.07495% | 0.33094% | 0.13557% | 0.52820% | 0.12548% | 0.15009% | 0.15601% | 0.03909% | 0.17302% | 0.27317% | 0.23462% | 0.37848% | 0.08922% | 0.17917% |
| R | 0.68207% | 0.32025% | 0.20216% | 0.18065% | 0.57936% | 0.35289% | 0.16587% | 0.73240% | 0.30002% | 1.16894% | 0.27770% | 0.33217% | 0.34527% | 0.17302% | 0.19145% | 0.60454% | 0.51923% | 0.83761% | 0.19745% | 0.39652% |
| S | 1.07688% | 0.50561% | 0.31918% | 0.28522% | 0.91471% | 0.55716% | 0.26188% | 1.15633% | 0.47369% | 1.84555% | 0.43844% | 0.52444% | 0.54512% | 0.27317% | 0.60454% | 0.47723% | 0.81977% | 1.32244% | 0.31174% | 0.62604% |
| T | 0.92490% | 0.43426% | 0.27413% | 0.24496% | 0.78562% | 0.47853% | 0.22493% | 0.99314% | 0.40684% | 1.58510% | 0.37656% | 0.45043% | 0.46819% | 0.23462% | 0.51923% | 0.81977% | 0.35204% | 1.13581% | 0.26774% | 0.53769% |
| V | 1.49204% | 0.70054% | 0.44223% | 0.39517% | 1.26736% | 0.77196% | 0.36285% | 1.60213% | 0.65630% | 2.55706% | 0.60746% | 0.72662% | 0.75528% | 0.37848% | 0.83761% | 1.32244% | 1.13581% | 0.91613% | 0.43192% | 0.86739% |
| W | 0.35172% | 0.16514% | 0.10425% | 0.09315% | 0.29875% | 0.18197% | 0.08553% | 0.37767% | 0.15471% | 0.60278% | 0.14320% | 0.17129% | 0.17804% | 0.08922% | 0.19745% | 0.31174% | 0.26774% | 0.43192% | 0.05091% | 0.20447% |
| Y | 0.70633% | 0.33163% | 0.20935% | 0.18707% | 0.59996% | 0.36544% | 0.17177% | 0.75844% | 0.31069% | 1.21051% | 0.28757% | 0.34398% | 0.35755% | 0.17917% | 0.39652% | 0.62604% | 0.53769% | 0.86739% | 0.20447% | 0.20531% |
Transition Count |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 7458 | 2579 | 754 | 1155 | 3524 | 3671 | 953 | 4928 | 1853 | 8421 | 1966 | 1551 | 1945 | 1097 | 2168 | 7492 | 5256 | 7717 | 760 | 1836 |
| C | 2579 | 5682 | 275 | 327 | 1816 | 1074 | 328 | 2208 | 410 | 3631 | 988 | 596 | 543 | 273 | 522 | 2341 | 2214 | 2449 | 413 | 648 |
| D | 754 | 275 | 3612 | 1478 | 852 | 683 | 564 | 572 | 875 | 1091 | 346 | 1462 | 695 | 595 | 896 | 1134 | 922 | 720 | 250 | 706 |
| E | 1155 | 327 | 1478 | 827 | 762 | 1038 | 579 | 687 | 1335 | 1460 | 423 | 889 | 1147 | 752 | 1310 | 1851 | 1090 | 995 | 199 | 612 |
| F | 3524 | 1816 | 852 | 762 | 5964 | 2061 | 1141 | 5379 | 1078 | 10161 | 1931 | 1368 | 1196 | 877 | 1174 | 2853 | 3362 | 5943 | 1509 | 4402 |
| G | 3671 | 1074 | 683 | 1038 | 2061 | 3237 | 541 | 2159 | 991 | 4105 | 972 | 998 | 1374 | 693 | 1393 | 3590 | 2182 | 2951 | 606 | 1011 |
| H | 953 | 328 | 564 | 579 | 1141 | 541 | 552 | 802 | 1204 | 1524 | 399 | 1495 | 581 | 711 | 1551 | 1349 | 953 | 1106 | 220 | 1023 |
| I | 4928 | 2208 | 572 | 687 | 5379 | 2159 | 802 | 8544 | 1182 | 14187 | 3589 | 1161 | 1267 | 857 | 1364 | 3420 | 3870 | 12252 | 815 | 2255 |
| K | 1853 | 410 | 875 | 1335 | 1078 | 991 | 1204 | 1182 | 2520 | 2299 | 687 | 1306 | 879 | 1571 | 4830 | 2222 | 1731 | 1644 | 684 | 968 |
| L | 8421 | 3631 | 1091 | 1460 | 10161 | 4105 | 1524 | 14187 | 2299 | 16603 | 5514 | 2130 | 2514 | 1570 | 2680 | 5660 | 6353 | 15545 | 1476 | 4223 |
| M | 1966 | 988 | 346 | 423 | 1931 | 972 | 399 | 3589 | 687 | 5514 | 1104 | 618 | 877 | 512 | 925 | 1553 | 1970 | 3387 | 475 | 1009 |
| N | 1551 | 596 | 1462 | 889 | 1368 | 998 | 1495 | 1161 | 1306 | 2130 | 618 | 5646 | 695 | 782 | 1530 | 3173 | 2144 | 1462 | 374 | 1276 |
| P | 1945 | 543 | 695 | 1147 | 1196 | 1374 | 581 | 1267 | 879 | 2514 | 877 | 695 | 8060 | 693 | 1033 | 1814 | 1584 | 1872 | 266 | 639 |
| Q | 1097 | 273 | 595 | 752 | 877 | 693 | 711 | 857 | 1571 | 1570 | 512 | 782 | 693 | 459 | 2012 | 1489 | 1181 | 1157 | 485 | 684 |
| R | 2168 | 522 | 896 | 1310 | 1174 | 1393 | 1551 | 1364 | 4830 | 2680 | 925 | 1530 | 1033 | 2012 | 4945 | 2751 | 2171 | 1953 | 632 | 1062 |
| S | 7492 | 2341 | 1134 | 1851 | 2853 | 3590 | 1349 | 3420 | 2222 | 5660 | 1553 | 3173 | 1814 | 1489 | 2751 | 5467 | 4861 | 4613 | 880 | 2089 |
| T | 5256 | 2214 | 922 | 1090 | 3362 | 2182 | 953 | 3870 | 1731 | 6353 | 1970 | 2144 | 1584 | 1181 | 2171 | 4861 | 3401 | 5405 | 586 | 2108 |
| V | 7717 | 2449 | 720 | 995 | 5943 | 2951 | 1106 | 12252 | 1644 | 15545 | 3387 | 1462 | 1872 | 1157 | 1953 | 4613 | 5405 | 8442 | 923 | 2562 |
| W | 760 | 413 | 250 | 199 | 1509 | 606 | 220 | 815 | 684 | 1476 | 475 | 374 | 266 | 485 | 632 | 880 | 586 | 923 | 4533 | 960 |
| Y | 1836 | 648 | 706 | 612 | 4402 | 1011 | 1023 | 2255 | 968 | 4223 | 1009 | 1276 | 639 | 684 | 1062 | 2089 | 2108 | 2562 | 960 | 6631 |
Number of Amino Acids in Alignment |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 1312 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| C | - | 600 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| D | - | - | 408 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| E | - | - | - | 415 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| F | - | - | - | - | 1059 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| G | - | - | - | - | - | 735 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| H | - | - | - | - | - | - | 340 | - | - | - | - | - | - | - | - | - | - | - | - | - |
| I | - | - | - | - | - | - | - | 1340 | - | - | - | - | - | - | - | - | - | - | - | - |
| K | - | - | - | - | - | - | - | - | 618 | - | - | - | - | - | - | - | - | - | - | - |
| L | - | - | - | - | - | - | - | - | - | 2158 | - | - | - | - | - | - | - | - | - | - |
| M | - | - | - | - | - | - | - | - | - | - | 520 | - | - | - | - | - | - | - | - | - |
| N | - | - | - | - | - | - | - | - | - | - | - | 654 | - | - | - | - | - | - | - | - |
| P | - | - | - | - | - | - | - | - | - | - | - | - | 711 | - | - | - | - | - | - | - |
| Q | - | - | - | - | - | - | - | - | - | - | - | - | - | 367 | - | - | - | - | - | - |
| R | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 782 | - | - | - | - | - |
| S | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1227 | - | - | - | - |
| T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1011 | - | - | - |
| V | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 1559 | - | - |
| W | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 370 | - |
| Y | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 733 |
Percentage of Amino Acids in Alignment |
| A | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | |
| A | 7.75% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| C | - | 3.54% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| D | - | - | 2.41% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| E | - | - | - | 2.45% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| F | - | - | - | - | 6.25% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| G | - | - | - | - | - | 4.34% | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| H | - | - | - | - | - | - | 2.00% | - | - | - | - | - | - | - | - | - | - | - | - | - |
| I | - | - | - | - | - | - | - | 7.92% | - | - | - | - | - | - | - | - | - | - | - | - |
| K | - | - | - | - | - | - | - | - | 3.65% | - | - | - | - | - | - | - | - | - | - | - |
| L | - | - | - | - | - | - | - | - | - | 12.7% | - | - | - | - | - | - | - | - | - | - |
| M | - | - | - | - | - | - | - | - | - | - | 3.07% | - | - | - | - | - | - | - | - | - |
| N | - | - | - | - | - | - | - | - | - | - | - | 3.86% | - | - | - | - | - | - | - | - |
| P | - | - | - | - | - | - | - | - | - | - | - | - | 4.20% | - | - | - | - | - | - | - |
| Q | - | - | - | - | - | - | - | - | - | - | - | - | - | 2.16% | - | - | - | - | - | - |
| R | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4.62% | - | - | - | - | - |
| S | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.25% | - | - | - | - |
| T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 5.97% | - | - | - |
| V | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 9.21% | - | - |
| W | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 2.18% | - |
| Y | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4.33% |