Blosum Log2 No Clustering

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	6	2	-11	-9	-18	-2	-7	-10	-12	-7	-11	-11	-2	-11	-9	-2	-4	-7	-16	-16
C	2	12	-21	-18	-12	-12	-15	-7	-15	1	-6	-17	-14	-5	-11	-7	-11	-7	-8	-10
D	-11	-21	8	0	-14	-10	4	-17	-6	-15	-14	0	-2	-6	-8	-6	-6	-13	-21	-12
E	-9	-18	0	7	-16	-11	-5	-8	-4	-15	-15	-4	-7	-1	-12	-5	-6	-5	-34	-18
F	-18	-12	-14	-16	9	-17	-10	-2	-18	-7	-6	-16	-10	-11	-15	-7	-4	-12	-11	-1
G	-2	-12	-10	-11	-17	7	-2	-17	-11	-5	-22	-2	-13	-13	-10	-5	-8	-14	-14	-20
H	-7	-15	4	-5	-10	-2	13	-11	2	-10	-17	2	-7	0	1	-9	-6	-11	-12	-2
I	-10	-7	-17	-8	-2	-17	-11	8	-14	-2	-2	-12	-7	-13	-7	-4	-7	1	-22	-11
K	-12	-15	-6	-4	-18	-11	2	-14	9	-8	-10	-6	-10	-4	2	-8	-10	-11	-18	-13
L	-7	1	-15	-15	-7	-5	-10	-2	-8	7	4	-16	-9	-14	-5	-5	-11	-4	-13	-12
M	-11	-6	-14	-15	-6	-22	-17	-2	-10	4	11	-15	-13	-13	-12	-7	-12	2	-10	-15
N	-11	-17	0	-4	-16	-2	2	-12	-6	-16	-15	10	-9	-6	-10	-1	-4	-10	-19	-11
P	-2	-14	-2	-7	-10	-13	-7	-7	-10	-9	-13	-9	7	-8	-9	-6	-5	-4	-31	-11
Q	-11	-5	-6	-1	-11	-13	0	-13	-4	-14	-13	-6	-8	11	-9	-9	-11	-7	-15	-16
R	-9	-11	-8	-12	-15	-10	1	-7	2	-5	-12	-10	-9	-9	8	-10	-15	-13	-14	-11
S	-2	-7	-6	-5	-7	-5	-9	-4	-8	-5	-7	-1	-6	-9	-10	8	-4	-5	-14	-13
T	-4	-11	-6	-6	-4	-8	-6	-7	-10	-11	-12	-4	-5	-11	-15	-4	6	-4	-13	-14
V	-7	-7	-13	-5	-12	-14	-11	1	-11	-4	2	-10	-4	-7	-13	-5	-4	7	-12	-12
W	-16	-8	-21	-34	-11	-14	-12	-22	-18	-13	-10	-19	-31	-15	-14	-14	-13	-12	12	-2
Y	-16	-10	-12	-18	-1	-20	-2	-11	-13	-12	-15	-11	-11	-16	-11	-13	-14	-12	-2	8

Blosum LN No Clustering

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	4	1	-7	-7	-12	-2	-5	-7	-8	-5	-8	-7	-1	-8	-7	-1	-3	-5	-11	-11
C	1	8	-15	-12	-8	-8	-11	-5	-11	1	-4	-12	-10	-3	-8	-5	-8	-5	-6	-7
D	-7	-15	5	0	-10	-7	3	-12	-4	-11	-10	0	-2	-4	-6	-4	-4	-9	-14	-9
E	-7	-12	0	5	-11	-8	-4	-5	-3	-10	-10	-3	-5	-1	-9	-4	-4	-3	-23	-12
F	-12	-8	-10	-11	6	-12	-7	-1	-12	-5	-4	-11	-7	-8	-10	-5	-3	-8	-8	-1
G	-2	-8	-7	-8	-12	5	-2	-12	-8	-4	-15	-1	-9	-9	-7	-3	-5	-10	-10	-14
H	-5	-11	3	-4	-7	-2	9	-8	2	-7	-12	1	-5	0	1	-7	-4	-8	-8	-2
I	-7	-5	-12	-5	-1	-12	-8	6	-10	-1	-1	-8	-5	-9	-5	-3	-5	1	-15	-8
K	-8	-11	-4	-3	-12	-8	2	-10	6	-5	-7	-4	-7	-3	2	-6	-7	-8	-13	-9
L	-5	1	-11	-10	-5	-4	-7	-1	-5	5	3	-11	-6	-10	-3	-3	-8	-3	-9	-9
M	-8	-4	-10	-10	-4	-15	-12	-1	-7	3	8	-10	-9	-9	-8	-5	-8	1	-7	-11
N	-7	-12	0	-3	-11	-1	1	-8	-4	-11	-10	7	-6	-4	-7	-1	-3	-7	-13	-7
P	-1	-10	-2	-5	-7	-9	-5	-5	-7	-6	-9	-6	5	-6	-6	-4	-3	-3	-22	-7
Q	-8	-3	-4	-1	-8	-9	0	-9	-3	-10	-9	-4	-6	8	-6	-6	-7	-5	-10	-11
R	-7	-8	-6	-9	-10	-7	1	-5	2	-3	-8	-7	-6	-6	6	-7	-10	-9	-10	-8
S	-1	-5	-4	-4	-5	-3	-7	-3	-6	-3	-5	-1	-4	-6	-7	6	-3	-3	-10	-9
T	-3	-8	-4	-4	-3	-5	-4	-5	-7	-8	-8	-3	-3	-7	-10	-3	4	-3	-9	-10
V	-5	-5	-9	-3	-8	-10	-8	1	-8	-3	1	-7	-3	-5	-9	-3	-3	5	-8	-9
W	-11	-6	-14	-23	-8	-10	-8	-15	-13	-9	-7	-13	-22	-10	-10	-10	-9	-8	8	-1
Y	-11	-7	-9	-12	-1	-14	-2	-8	-9	-9	-11	-7	-7	-11	-8	-9	-10	-9	-1	5

Blosum Log10 No Clustering

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	2	1	-3	-3	-5	-1	-2	-3	-4	-2	-3	-3	-1	-3	-3	-1	-1	-2	-5	-5
C	1	4	-6	-5	-3	-4	-5	-2	-5	0	-2	-5	-4	-2	-3	-2	-3	-2	-2	-3
D	-3	-6	2	0	-4	-3	1	-5	-2	-5	-4	0	-1	-2	-3	-2	-2	-4	-6	-4
E	-3	-5	0	2	-5	-3	-2	-2	-1	-4	-4	-1	-2	0	-4	-2	-2	-1	-10	-5
F	-5	-3	-4	-5	3	-5	-3	0	-5	-2	-2	-5	-3	-3	-4	-2	-1	-3	-3	0
G	-1	-4	-3	-3	-5	2	-1	-5	-3	-2	-7	-1	-4	-4	-3	-1	-2	-4	-4	-6
H	-2	-5	1	-2	-3	-1	4	-3	1	-3	-5	0	-2	0	0	-3	-2	-3	-4	-1
I	-3	-2	-5	-2	0	-5	-3	2	-4	-1	0	-4	-2	-4	-2	-1	-2	0	-7	-3
K	-4	-5	-2	-1	-5	-3	1	-4	3	-2	-3	-2	-3	-1	1	-3	-3	-3	-6	-4
L	-2	0	-5	-4	-2	-2	-3	-1	-2	2	1	-5	-3	-4	-1	-2	-3	-1	-4	-4
M	-3	-2	-4	-4	-2	-7	-5	0	-3	1	3	-4	-4	-4	-4	-2	-3	0	-3	-5
N	-3	-5	0	-1	-5	-1	0	-4	-2	-5	-4	3	-3	-2	-3	0	-1	-3	-6	-3
P	-1	-4	-1	-2	-3	-4	-2	-2	-3	-3	-4	-3	2	-3	-3	-2	-1	-1	-9	-3
Q	-3	-2	-2	0	-3	-4	0	-4	-1	-4	-4	-2	-3	3	-3	-3	-3	-2	-4	-5
R	-3	-3	-3	-4	-4	-3	0	-2	1	-1	-4	-3	-3	-3	3	-3	-5	-4	-4	-3
S	-1	-2	-2	-2	-2	-1	-3	-1	-3	-2	-2	0	-2	-3	-3	2	-1	-1	-4	-4
T	-1	-3	-2	-2	-1	-2	-2	-2	-3	-3	-3	-1	-1	-3	-5	-1	2	-1	-4	-4
V	-2	-2	-4	-1	-3	-4	-3	0	-3	-1	0	-3	-1	-2	-4	-1	-1	2	-4	-4
W	-5	-2	-6	-10	-3	-4	-4	-7	-6	-4	-3	-6	-9	-4	-4	-4	-4	-4	4	-1
Y	-5	-3	-4	-5	0	-6	-1	-3	-4	-4	-5	-3	-3	-5	-3	-4	-4	-4	-1	2

Distance Log2

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	3	7	11	10	15	6	13	11	12	8	14	12	6	13	10	7	7	8	15	13
C	7	6	19	17	15	15	20	13	17	8	15	19	16	13	15	12	14	12	15	13
D	11	19	3	6	14	11	8	15	10	13	16	7	7	11	11	10	9	12	18	12
E	10	17	6	3	14	11	12	10	8	13	16	9	9	8	12	9	8	8	25	15
F	15	15	14	14	4	15	15	8	16	9	13	16	12	14	14	11	8	12	14	7
G	6	15	11	11	15	3	11	15	12	8	20	8	13	14	11	9	9	12	15	16
H	13	20	8	12	15	11	8	16	9	14	21	10	13	12	10	15	12	15	18	11
I	11	13	15	10	8	15	16	4	14	7	10	14	10	15	10	9	9	6	19	12
K	12	17	10	8	16	12	9	14	4	10	14	11	12	10	6	11	11	12	18	13
L	8	8	13	13	9	8	14	7	10	3	6	15	10	14	8	9	11	7	14	12
M	14	15	16	16	13	20	21	10	14	6	7	18	15	17	15	13	14	8	16	16
N	12	19	7	9	16	8	10	14	11	15	18	5	12	12	13	8	9	12	19	13
P	6	16	7	9	12	13	13	10	12	10	15	12	3	12	11	10	8	8	23	11
Q	13	13	11	8	14	14	12	15	10	14	17	12	12	5	13	13	12	11	17	16
R	10	15	11	12	14	11	10	10	6	8	15	13	11	13	4	12	13	12	15	12
S	7	12	10	9	11	9	15	9	11	9	13	8	10	13	12	4	8	8	16	13
T	7	14	9	8	8	9	12	9	11	11	14	9	8	12	13	8	3	7	14	12
V	8	12	12	8	12	12	15	6	12	7	8	12	8	11	12	8	7	3	14	12
W	15	15	18	25	14	15	18	19	18	14	16	19	23	17	15	16	14	14	5	9
Y	13	13	12	15	7	16	11	12	13	12	16	13	11	16	12	13	12	12	9	3

Distance LN

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	1	5	7	6	10	4	8	7	8	5	9	8	4	8	7	4	4	6	10	9
C	5	4	13	12	10	10	14	8	12	5	10	13	11	9	10	8	9	8	10	9
D	7	13	2	4	9	7	5	10	7	9	11	5	5	7	7	6	6	8	12	8
E	6	12	4	2	10	7	8	7	6	9	11	6	6	5	8	6	5	5	17	10
F	10	10	9	10	2	10	10	5	11	6	8	11	8	9	10	7	5	8	9	5
G	4	10	7	7	10	2	7	10	8	5	13	5	8	10	8	6	6	8	10	10
H	8	14	5	8	10	7	5	11	6	10	14	7	9	8	6	10	8	10	12	7
I	7	8	10	7	5	10	11	2	10	5	7	9	7	10	7	6	6	4	13	8
K	8	12	7	6	11	8	6	10	2	7	10	8	8	7	4	7	7	8	12	9
L	5	5	9	9	6	5	10	5	7	2	4	10	7	10	6	6	7	5	10	8
M	9	10	11	11	8	13	14	7	10	4	4	12	10	12	10	9	9	5	11	11
N	8	13	5	6	11	5	7	9	8	10	12	3	8	8	8	6	6	8	13	8
P	4	11	5	6	8	8	9	7	8	7	10	8	2	8	7	6	5	5	16	7
Q	8	9	7	5	9	10	8	10	7	10	12	8	8	3	8	9	8	7	12	11
R	7	10	7	8	10	8	6	7	4	6	10	8	7	8	2	8	9	8	10	8
S	4	8	6	6	7	6	10	6	7	6	9	6	6	9	8	2	5	6	10	9
T	4	9	6	5	5	6	8	6	7	7	9	6	5	8	9	5	1	4	9	8
V	6	8	8	5	8	8	10	4	8	5	5	8	5	7	8	6	4	2	9	8
W	10	10	12	17	9	10	12	13	12	10	11	13	16	12	10	10	9	9	3	6
Y	9	9	8	10	5	10	7	8	9	8	11	8	7	11	8	9	8	8	6	2

Distance Log10

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	0	1	3	2	4	1	3	3	3	2	3	3	1	3	2	1	1	2	4	3
C	1	1	5	5	4	4	5	3	4	2	4	5	4	3	4	3	3	3	4	3
D	3	5	0	1	3	3	2	4	2	3	4	2	1	3	2	2	2	3	5	3
E	2	5	1	0	4	3	3	2	2	3	4	2	2	2	3	2	2	2	7	4
F	4	4	3	4	0	4	4	2	4	2	3	4	3	3	4	3	2	3	4	1
G	1	4	3	3	4	0	3	4	3	2	5	2	3	4	3	2	2	3	4	4
H	3	5	2	3	4	3	2	4	2	4	6	2	3	3	2	4	3	4	5	3
I	3	3	4	2	2	4	4	0	4	1	2	3	2	4	2	2	2	1	5	3
K	3	4	2	2	4	3	2	4	0	2	4	3	3	2	1	3	3	3	5	3
L	2	2	3	3	2	2	4	1	2	0	1	4	2	4	2	2	2	1	4	3
M	3	4	4	4	3	5	6	2	4	1	1	5	4	4	4	3	3	2	4	4
N	3	5	2	2	4	2	2	3	3	4	5	1	3	3	3	2	2	3	5	3
P	1	4	1	2	3	3	3	2	3	2	4	3	0	3	2	2	2	2	6	3
Q	3	3	3	2	3	4	3	4	2	4	4	3	3	1	3	3	3	3	4	4
R	2	4	2	3	4	3	2	2	1	2	4	3	2	3	0	3	3	3	4	3
S	1	3	2	2	3	2	4	2	3	2	3	2	2	3	3	0	2	2	4	3
T	1	3	2	2	2	2	3	2	3	2	3	2	2	3	3	2	0	1	3	3
V	2	3	3	2	3	3	4	1	3	1	2	3	2	3	3	2	1	0	3	3
W	4	4	5	7	4	4	5	5	5	4	4	5	6	4	4	4	3	3	1	2
Y	3	3	3	4	1	4	3	3	3	3	4	3	3	4	3	3	3	3	2	0

Observed Probability of Transition

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	8.79229%	0.40766%	0.03070%	0.06029%	0.00194%	0.62420%	0.00810%	0.02614%	0.01366%	0.17117%	0.00415%	0.01254%	0.75781%	0.00827%	0.03824%	0.49776%	0.46036%	0.14972%	0.00135%	0.00477%
C	0.40766%	0.61352%	0.00007%	0.00030%	0.00148%	0.00194%	0.00004%	0.00790%	0.00036%	0.23346%	0.00209%	0.00012%	0.00095%	0.00583%	0.00206%	0.00937%	0.00396%	0.01519%	0.00184%	0.00451%
D	0.03070%	0.00007%	4.85667%	0.86683%	0.00356%	0.02853%	0.20300%	0.00160%	0.05235%	0.00455%	0.00080%	0.28419%	0.32909%	0.02847%	0.03177%	0.06589%	0.13734%	0.00925%	0.00015%	0.01106%
E	0.06029%	0.00030%	0.86683%	6.52918%	0.00232%	0.02118%	0.01088%	0.04445%	0.14352%	0.00704%	0.00077%	0.07638%	0.07487%	0.15739%	0.00981%	0.12078%	0.20488%	0.22234%	0.00000%	0.00199%
F	0.00194%	0.00148%	0.00356%	0.00232%	3.82121%	0.00172%	0.00126%	0.21451%	0.00068%	0.07414%	0.00824%	0.00070%	0.01507%	0.00339%	0.00249%	0.03078%	0.18970%	0.01232%	0.00312%	0.38136%
G	0.62420%	0.00194%	0.02853%	0.02118%	0.00172%	6.24311%	0.02624%	0.00158%	0.01235%	0.19698%	0.00005%	0.15341%	0.00843%	0.00234%	0.01787%	0.12439%	0.08914%	0.00922%	0.00176%	0.00103%
H	0.00810%	0.00004%	0.20300%	0.01088%	0.00126%	0.02624%	0.19153%	0.00081%	0.07806%	0.00238%	0.00002%	0.03525%	0.00455%	0.01470%	0.06022%	0.00154%	0.01096%	0.00148%	0.00021%	0.02710%
I	0.02614%	0.00790%	0.00160%	0.04445%	0.21451%	0.00158%	0.00081%	3.32948%	0.00266%	0.37581%	0.04348%	0.00325%	0.04717%	0.00196%	0.04179%	0.08960%	0.08936%	1.01406%	0.00007%	0.01186%
K	0.01366%	0.00036%	0.05235%	0.14352%	0.00068%	0.01235%	0.07806%	0.00266%	3.25777%	0.04385%	0.00248%	0.01973%	0.01547%	0.03596%	0.84777%	0.02081%	0.02082%	0.01241%	0.00022%	0.00655%
L	0.17117%	0.23346%	0.00455%	0.00704%	0.07414%	0.19698%	0.00238%	0.37581%	0.04385%	6.99048%	0.63176%	0.00137%	0.04603%	0.00244%	0.14718%	0.13789%	0.03352%	0.34077%	0.00262%	0.01534%
M	0.00415%	0.00209%	0.00080%	0.00077%	0.00824%	0.00005%	0.00002%	0.04348%	0.00248%	0.63176%	0.41469%	0.00023%	0.00119%	0.00035%	0.00132%	0.00722%	0.00321%	0.24024%	0.00092%	0.00055%
N	0.01254%	0.00012%	0.28419%	0.07638%	0.00070%	0.15341%	0.03525%	0.00325%	0.01973%	0.00137%	0.00023%	1.89500%	0.01311%	0.00922%	0.00762%	0.14280%	0.11491%	0.01066%	0.00010%	0.00766%
P	0.75781%	0.00095%	0.32909%	0.07487%	0.01507%	0.00843%	0.00455%	0.04717%	0.01547%	0.04603%	0.00119%	0.01311%	5.55177%	0.01248%	0.03275%	0.06816%	0.24011%	0.24013%	0.00000%	0.02133%
Q	0.00827%	0.00583%	0.02847%	0.15739%	0.00339%	0.00234%	0.01470%	0.00196%	0.03596%	0.00244%	0.00035%	0.00922%	0.01248%	1.57498%	0.00765%	0.00686%	0.00864%	0.02135%	0.00035%	0.00088%
R	0.03824%	0.00206%	0.03177%	0.00981%	0.00249%	0.01787%	0.06022%	0.04179%	0.84777%	0.14718%	0.00132%	0.00762%	0.03275%	0.00765%	4.22008%	0.01280%	0.00530%	0.00949%	0.00132%	0.01306%
S	0.49776%	0.00937%	0.06589%	0.12078%	0.03078%	0.12439%	0.00154%	0.08960%	0.02081%	0.13789%	0.00722%	0.14280%	0.06816%	0.00686%	0.01280%	3.87829%	0.21251%	0.14905%	0.00106%	0.00629%
T	0.46036%	0.00396%	0.13734%	0.20488%	0.18970%	0.08914%	0.01096%	0.08936%	0.02082%	0.03352%	0.00321%	0.11491%	0.24011%	0.00864%	0.00530%	0.21251%	8.79811%	0.41173%	0.00379%	0.00952%
V	0.14972%	0.01519%	0.00925%	0.22234%	0.01232%	0.00922%	0.00148%	1.01406%	0.01241%	0.34077%	0.24024%	0.01066%	0.24013%	0.02135%	0.00949%	0.14905%	0.41173%	6.28606%	0.00431%	0.01438%
W	0.00135%	0.00184%	0.00015%	0.00000%	0.00312%	0.00176%	0.00021%	0.00007%	0.00022%	0.00262%	0.00092%	0.00010%	0.00000%	0.00035%	0.00132%	0.00106%	0.00379%	0.00431%	1.58399%	0.10922%
Y	0.00477%	0.00451%	0.01106%	0.00199%	0.38136%	0.00103%	0.02710%	0.01186%	0.00655%	0.01534%	0.00055%	0.00766%	0.02133%	0.00088%	0.01306%	0.00629%	0.00952%	0.01438%	0.10922%	6.33003%

Expected Probability of Transition

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	1.08821%	0.20094%	1.23122%	1.57357%	0.89622%	1.44048%	0.09075%	0.90517%	0.81840%	1.71595%	0.18553%	0.48855%	1.35950%	0.36287%	1.01508%	0.98707%	2.07029%	1.61278%	0.34430%	1.38832%
C	0.20094%	0.00927%	0.11367%	0.14528%	0.08274%	0.13299%	0.00837%	0.08357%	0.07556%	0.15842%	0.01713%	0.04510%	0.12551%	0.03350%	0.09372%	0.09113%	0.19114%	0.14890%	0.03178%	0.12818%
D	1.23122%	0.11367%	0.34825%	0.89018%	0.50700%	0.81489%	0.05133%	0.51206%	0.46297%	0.97072%	0.10495%	0.27638%	0.76908%	0.20528%	0.57424%	0.55839%	1.17118%	0.91236%	0.19477%	0.78538%
E	1.57357%	0.14528%	0.89018%	0.56885%	0.64797%	1.04148%	0.06561%	0.65444%	0.59171%	1.24064%	0.13414%	0.35323%	0.98293%	0.26236%	0.73391%	0.71366%	1.49684%	1.16605%	0.24893%	1.00377%
F	0.89622%	0.08274%	0.50700%	0.64797%	0.18452%	0.59317%	0.03736%	0.37273%	0.33700%	0.70660%	0.07640%	0.20118%	0.55982%	0.14942%	0.41799%	0.40646%	0.85251%	0.66412%	0.14177%	0.57169%
G	1.44048%	0.13299%	0.81489%	1.04148%	0.59317%	0.47669%	0.06006%	0.59909%	0.54166%	1.13571%	0.12279%	0.32335%	0.89979%	0.24017%	0.67184%	0.65330%	1.37024%	1.06743%	0.22787%	0.91887%
H	0.09075%	0.00837%	0.05133%	0.06561%	0.03736%	0.06006%	0.00189%	0.03774%	0.03412%	0.07154%	0.00773%	0.02037%	0.05668%	0.01513%	0.04232%	0.04115%	0.08632%	0.06724%	0.01435%	0.05788%
I	0.90517%	0.08357%	0.51206%	0.65444%	0.37273%	0.59909%	0.03774%	0.18823%	0.34037%	0.71366%	0.07716%	0.20319%	0.56541%	0.15092%	0.42217%	0.41052%	0.86103%	0.67075%	0.14319%	0.57740%
K	0.81840%	0.07556%	0.46297%	0.59171%	0.33700%	0.54166%	0.03412%	0.34037%	0.15387%	0.64525%	0.06976%	0.18371%	0.51121%	0.13645%	0.38170%	0.37117%	0.77849%	0.60645%	0.12946%	0.52205%
L	1.71595%	0.15842%	0.97072%	1.24064%	0.70660%	1.13571%	0.07154%	0.71366%	0.64525%	0.67645%	0.14628%	0.38519%	1.07186%	0.28610%	0.80032%	0.77823%	1.63227%	1.27156%	0.27145%	1.09459%
M	0.18553%	0.01713%	0.10495%	0.13414%	0.07640%	0.12279%	0.00773%	0.07716%	0.06976%	0.14628%	0.00790%	0.04164%	0.11589%	0.03093%	0.08653%	0.08414%	0.17648%	0.13748%	0.02935%	0.11835%
N	0.48855%	0.04510%	0.27638%	0.35323%	0.20118%	0.32335%	0.02037%	0.20319%	0.18371%	0.38519%	0.04164%	0.05483%	0.30517%	0.08145%	0.22786%	0.22157%	0.46473%	0.36203%	0.07728%	0.31164%
P	1.35950%	0.12551%	0.76908%	0.98293%	0.55982%	0.89979%	0.05668%	0.56541%	0.51121%	1.07186%	0.11589%	0.30517%	0.42460%	0.22667%	0.63407%	0.61657%	1.29320%	1.00742%	0.21506%	0.86721%
Q	0.36287%	0.03350%	0.20528%	0.26236%	0.14942%	0.24017%	0.01513%	0.15092%	0.13645%	0.28610%	0.03093%	0.08145%	0.22667%	0.03025%	0.16924%	0.16457%	0.34518%	0.26890%	0.05740%	0.23147%
R	1.01508%	0.09372%	0.57424%	0.73391%	0.41799%	0.67184%	0.04232%	0.42217%	0.38170%	0.80032%	0.08653%	0.22786%	0.63407%	0.16924%	0.23671%	0.46037%	0.96558%	0.75220%	0.16058%	0.64751%
S	0.98707%	0.09113%	0.55839%	0.71366%	0.40646%	0.65330%	0.04115%	0.41052%	0.37117%	0.77823%	0.08414%	0.22157%	0.61657%	0.16457%	0.46037%	0.22383%	0.93894%	0.73144%	0.15615%	0.62964%
T	2.07029%	0.19114%	1.17118%	1.49684%	0.85251%	1.37024%	0.08632%	0.86103%	0.77849%	1.63227%	0.17648%	0.46473%	1.29320%	0.34518%	0.96558%	0.93894%	0.98466%	1.53413%	0.32751%	1.32062%
V	1.61278%	0.14890%	0.91236%	1.16605%	0.66412%	1.06743%	0.06724%	0.67075%	0.60645%	1.27156%	0.13748%	0.36203%	1.00742%	0.26890%	0.75220%	0.73144%	1.53413%	0.59755%	0.25513%	1.02878%
W	0.34430%	0.03178%	0.19477%	0.24893%	0.14177%	0.22787%	0.01435%	0.14319%	0.12946%	0.27145%	0.02935%	0.07728%	0.21506%	0.05740%	0.16058%	0.15615%	0.32751%	0.25513%	0.02723%	0.21962%
Y	1.38832%	0.12818%	0.78538%	1.00377%	0.57169%	0.91887%	0.05788%	0.57740%	0.52205%	1.09459%	0.11835%	0.31164%	0.86721%	0.23147%	0.64751%	0.62964%	1.32062%	1.02878%	0.21962%	0.44280%

Transition Count

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	495682131	22982867	1731283	3399363	109768	35190923	456970	1473708	770172	9650437	234482	706986	42723049	466303	2155894	28062524	25953945	8441094	76278	269383
C	22982867	34588795	4034	17357	83697	109579	2430	445629	20296	13161867	117800	6854	53622	328891	116580	528234	223665	856676	104184	254505
D	1731283	4034	273803926	48869236	201233	1608610	11444771	90382	2951510	256611	45398	16021927	18553485	1605200	1791264	3715156	7743028	521973	8654	623848
E	3399363	17357	48869236	368094896	131259	1194390	613432	2506114	8091583	397392	43682	4306532	4221431	8873562	553034	6809286	11550588	12535011	114	112724
F	109768	83697	201233	131259	215427902	97003	71437	12093846	38483	4179900	464567	39990	849675	191339	140524	1735738	10695167	694667	176202	21500188
G	35190923	109579	1608610	1194390	97003	351967015	1479354	89187	696727	11105579	2995	8649120	475469	132297	1007929	7012806	5025458	520122	99321	58535
H	456970	2430	11444771	613432	71437	1479354	10798012	45855	4400787	134187	1169	1987326	256670	828892	3395415	87246	618261	83619	12213	1528205
I	1473708	445629	90382	2506114	12093846	89187	45855	187705814	149992	21187278	2451760	183652	2659696	111023	2356196	5051819	5038368	57169515	4151	668947
K	770172	20296	2951510	8091583	38483	696727	4400787	149992	183663127	2472156	140014	1112778	872652	2027307	47794792	1173211	1173796	699981	12821	369716
L	9650437	13161867	256611	397392	4179900	11105579	134187	21187278	2472156	394101498	35616674	77544	2595554	137746	8297705	7774072	1890028	19211584	148132	865070
M	234482	117800	45398	43682	464567	2995	1169	2451760	140014	35616674	23379047	13392	67537	20145	74776	407047	181464	13544178	52279	31458
N	706986	6854	16021927	4306532	39990	8649120	1987326	183652	1112778	77544	13392	106834570	739543	520267	429910	8050668	6478452	601061	6127	432295
P	42723049	53622	18553485	4221431	849675	475469	256670	2659696	872652	2595554	67537	739543	312991865	703789	1846377	3843099	13536899	13538048	250	1202954
Q	466303	328891	1605200	8873562	191339	132297	828892	111023	2027307	137746	20145	520267	703789	88792665	431671	386882	487343	1203793	19786	49956
R	2155894	116580	1791264	553034	140524	1007929	3395415	2356196	47794792	8297705	74776	429910	1846377	431671	237915001	721929	299087	535026	74705	736392
S	28062524	528234	3715156	6809286	1735738	7012806	87246	5051819	1173211	7774072	407047	8050668	3843099	386882	721929	218646197	11981161	8403394	60011	354839
T	25953945	223665	7743028	11550588	10695167	5025458	618261	5038368	1173796	1890028	181464	6478452	13536899	487343	299087	11981161	496010252	23212120	213950	537097
V	8441094	856676	521973	12535011	694667	520122	83619	57169515	699981	19211584	13544178	601061	13538048	1203793	535026	8403394	23212120	354388893	243127	811214
W	76278	104184	8654	114	176202	99321	12213	4151	12821	148132	52279	6127	250	19786	74705	60011	213950	243127	89300792	6157993
Y	269383	254505	623848	112724	21500188	58535	1528205	668947	369716	865070	31458	432295	1202954	49956	736392	354839	537097	811214	6157993	356867710

Number of Amino Acids in Alignment

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	124352	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
C	-	11405	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
D	-	-	70300	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
E	-	-	-	89756	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
F	-	-	-	-	50678	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
G	-	-	-	-	-	81971	-	-	-	-	-	-	-	-	-	-	-	-	-	-
H	-	-	-	-	-	-	5168	-	-	-	-	-	-	-	-	-	-	-	-	-
I	-	-	-	-	-	-	-	51371	-	-	-	-	-	-	-	-	-	-	-	-
K	-	-	-	-	-	-	-	-	47249	-	-	-	-	-	-	-	-	-	-	-
L	-	-	-	-	-	-	-	-	-	97833	-	-	-	-	-	-	-	-	-	-
M	-	-	-	-	-	-	-	-	-	-	10555	-	-	-	-	-	-	-	-	-
N	-	-	-	-	-	-	-	-	-	-	-	27718	-	-	-	-	-	-	-	-
P	-	-	-	-	-	-	-	-	-	-	-	-	77745	-	-	-	-	-	-	-
Q	-	-	-	-	-	-	-	-	-	-	-	-	-	20791	-	-	-	-	-	-
R	-	-	-	-	-	-	-	-	-	-	-	-	-	-	57772	-	-	-	-	-
S	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	56193	-	-	-	-
T	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	119454	-	-	-
V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	91634	-	-
W	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	19684	-
Y	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	80339

Percentage of Amino Acids in Alignment

	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
A	10.4%	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
C	-	0.95%	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
D	-	-	5.89%	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
E	-	-	-	7.53%	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
F	-	-	-	-	4.25%	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
G	-	-	-	-	-	6.87%	-	-	-	-	-	-	-	-	-	-	-	-	-	-
H	-	-	-	-	-	-	0.43%	-	-	-	-	-	-	-	-	-	-	-	-	-
I	-	-	-	-	-	-	-	4.30%	-	-	-	-	-	-	-	-	-	-	-	-
K	-	-	-	-	-	-	-	-	3.96%	-	-	-	-	-	-	-	-	-	-	-
L	-	-	-	-	-	-	-	-	-	8.20%	-	-	-	-	-	-	-	-	-	-
M	-	-	-	-	-	-	-	-	-	-	0.88%	-	-	-	-	-	-	-	-	-
N	-	-	-	-	-	-	-	-	-	-	-	2.32%	-	-	-	-	-	-	-	-
P	-	-	-	-	-	-	-	-	-	-	-	-	6.52%	-	-	-	-	-	-	-
Q	-	-	-	-	-	-	-	-	-	-	-	-	-	1.74%	-	-	-	-	-	-
R	-	-	-	-	-	-	-	-	-	-	-	-	-	-	4.84%	-	-	-	-	-
S	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	4.71%	-	-	-	-
T	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	10.0%	-	-	-
V	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	7.68%	-	-
W	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1.65%	-
Y	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	6.74%