Immunoglobulin domain |
Blosum Log2 No Clustering |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 3 | 0 | -2 | -1 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | -1 | 0 | 0 | -1 | 0 | -1 | 2 | -4 | -2 | -1 |
| B | 0 | 8 | -6 | 1 | 1 | 0 | 0 | 1 | -2 | 1 | -1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | -2 | -1 | 6 |
| C | -2 | -6 | 9 | -7 | -7 | -4 | -6 | -6 | -4 | -5 | -5 | -6 | -6 | -6 | -6 | -5 | -5 | -5 | -3 | -9 | -6 | -7 |
| D | -1 | 1 | -7 | 4 | 1 | -2 | 1 | 1 | -2 | 0 | -2 | -1 | 2 | 0 | 0 | -1 | 0 | -1 | -2 | -4 | -2 | 3 |
| E | 0 | 1 | -7 | 1 | 2 | -1 | 0 | 1 | -1 | 0 | -1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | -1 | -3 | -2 | 1 |
| F | 0 | 0 | -4 | -2 | -1 | 3 | -1 | 0 | 1 | -1 | 2 | 1 | -1 | -1 | 0 | 0 | 0 | 0 | 0 | -1 | 2 | -2 |
| G | 0 | 0 | -6 | 1 | 0 | -1 | 4 | -1 | -3 | 0 | -3 | -2 | 0 | -1 | 0 | -1 | 0 | -1 | -2 | -5 | -1 | 2 |
| H | -1 | 1 | -6 | 1 | 1 | 0 | -1 | 2 | -1 | 1 | -1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | -1 | -3 | -1 | 0 |
| I | 0 | -2 | -4 | -2 | -1 | 1 | -3 | -1 | 3 | -1 | 2 | 1 | -1 | 0 | -1 | -1 | -1 | 0 | 1 | -3 | -1 | -2 |
| K | -1 | 1 | -5 | 0 | 0 | -1 | 0 | 1 | -1 | 2 | -1 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | -1 | -3 | -1 | 0 |
| L | 0 | -1 | -5 | -2 | -1 | 2 | -3 | -1 | 2 | -1 | 3 | 1 | -2 | -1 | -1 | -1 | -1 | -1 | 1 | 1 | -1 | -1 |
| M | 0 | 0 | -6 | -1 | 0 | 1 | -2 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -2 | -1 | -3 |
| N | -1 | 1 | -6 | 2 | 1 | -1 | 0 | 0 | -1 | 0 | -2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | -1 | -4 | -1 | 0 |
| P | 0 | 0 | -6 | 0 | 0 | -1 | -1 | 0 | 0 | 0 | -1 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | -1 | -4 | -2 | 0 |
| Q | 0 | 0 | -6 | 0 | 1 | 0 | 0 | 1 | -1 | 1 | -1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | -1 | -3 | -1 | 0 |
| R | -1 | 0 | -5 | -1 | 0 | 0 | -1 | 1 | -1 | 2 | -1 | 0 | 0 | 0 | 1 | 2 | 0 | 1 | -1 | -3 | -1 | 0 |
| S | 0 | 1 | -5 | 0 | 1 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | -1 | -3 | -1 | 1 |
| T | -1 | 0 | -5 | -1 | 0 | 0 | -1 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 0 | -3 | -1 | -1 |
| V | 2 | 0 | -3 | -2 | -1 | 0 | -2 | -1 | 1 | -1 | 1 | 1 | -1 | -1 | -1 | -1 | -1 | 0 | 2 | -3 | -1 | -2 |
| W | -4 | -2 | -9 | -4 | -3 | -1 | -5 | -3 | -3 | -3 | 1 | -2 | -4 | -4 | -3 | -3 | -3 | -3 | -3 | 9 | -3 | -5 |
| Y | -2 | -1 | -6 | -2 | -2 | 2 | -1 | -1 | -1 | -1 | -1 | -1 | -1 | -2 | -1 | -1 | -1 | -1 | -1 | -3 | 6 | -2 |
| Z | -1 | 6 | -7 | 3 | 1 | -2 | 2 | 0 | -2 | 0 | -1 | -3 | 0 | 0 | 0 | 0 | 1 | -1 | -2 | -5 | -2 | 10 |
Blosum LN No Clustering |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 2 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 1 | -3 | -1 | -1 |
| B | 0 | 5 | -4 | 1 | 0 | 0 | 0 | 1 | -1 | 0 | -1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | -2 | -1 | 4 |
| C | -1 | -4 | 6 | -5 | -5 | -3 | -4 | -4 | -3 | -4 | -4 | -4 | -4 | -4 | -4 | -4 | -4 | -4 | -2 | -6 | -4 | -5 |
| D | -1 | 1 | -5 | 3 | 1 | -1 | 1 | 1 | -1 | 0 | -2 | -1 | 1 | 0 | 0 | 0 | 0 | -1 | -1 | -2 | -2 | 2 |
| E | 0 | 0 | -5 | 1 | 1 | -1 | 0 | 1 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | -1 | -2 | -1 | 1 |
| F | 0 | 0 | -3 | -1 | -1 | 2 | -1 | 0 | 1 | 0 | 1 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -2 |
| G | 0 | 0 | -4 | 1 | 0 | -1 | 3 | 0 | -2 | 0 | -2 | -1 | 0 | -1 | 0 | -1 | 0 | -1 | -1 | -3 | -1 | 1 |
| H | 0 | 1 | -4 | 1 | 1 | 0 | 0 | 1 | -1 | 1 | -1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | -1 | -2 | -1 | 0 |
| I | 0 | -1 | -3 | -1 | -1 | 1 | -2 | -1 | 2 | -1 | 1 | 1 | -1 | 0 | -1 | -1 | -1 | 0 | 1 | -2 | 0 | -1 |
| K | -1 | 0 | -4 | 0 | 0 | 0 | 0 | 1 | -1 | 1 | -1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | -1 | -2 | -1 | 0 |
| L | 0 | -1 | -4 | -2 | -1 | 1 | -2 | -1 | 1 | -1 | 2 | 1 | -1 | -1 | -1 | -1 | -1 | -1 | 1 | 1 | -1 | -1 |
| M | 0 | 0 | -4 | -1 | 0 | 0 | -1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -1 | -1 | -2 |
| N | 0 | 1 | -4 | 1 | 0 | -1 | 0 | 0 | -1 | 0 | -1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | -1 | -3 | -1 | 0 |
| P | 0 | 0 | -4 | 0 | 0 | -1 | -1 | 0 | 0 | 0 | -1 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | -3 | -1 | 0 |
| Q | 0 | 0 | -4 | 0 | 0 | 0 | 0 | 1 | -1 | 0 | -1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | -1 | -2 | -1 | 0 |
| R | -1 | 0 | -4 | 0 | 0 | 0 | -1 | 1 | -1 | 1 | -1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | -2 | -1 | 0 |
| S | 0 | 0 | -4 | 0 | 1 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | -2 | -1 | 1 |
| T | 0 | 0 | -4 | -1 | 0 | 0 | -1 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | -2 | -1 | -1 |
| V | 1 | 0 | -2 | -1 | -1 | 0 | -1 | -1 | 1 | -1 | 1 | 1 | -1 | 0 | -1 | 0 | 0 | 0 | 2 | -2 | -1 | -1 |
| W | -3 | -2 | -6 | -2 | -2 | 0 | -3 | -2 | -2 | -2 | 1 | -1 | -3 | -3 | -2 | -2 | -2 | -2 | -2 | 6 | -2 | -4 |
| Y | -1 | -1 | -4 | -2 | -1 | 1 | -1 | -1 | 0 | -1 | -1 | -1 | -1 | -1 | -1 | -1 | -1 | -1 | -1 | -2 | 4 | -1 |
| Z | -1 | 4 | -5 | 2 | 1 | -2 | 1 | 0 | -1 | 0 | -1 | -2 | 0 | 0 | 0 | 0 | 1 | -1 | -1 | -4 | -1 | 7 |
Blosum Log10 No Clustering |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -1 | 0 | 0 |
| B | 0 | 2 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 2 |
| C | 0 | -2 | 3 | -2 | -2 | -1 | -2 | -2 | -1 | -2 | -2 | -2 | -2 | -2 | -2 | -2 | -2 | -2 | -1 | -3 | -2 | -2 |
| D | 0 | 0 | -2 | 1 | 0 | 0 | 0 | 0 | -1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | -1 | -1 | 1 |
| E | 0 | 0 | -2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | -1 | 0 |
| F | 0 | 0 | -1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -1 |
| G | 0 | 0 | -2 | 0 | 0 | 0 | 1 | 0 | -1 | 0 | -1 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | -1 | 0 | 0 |
| H | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 |
| I | 0 | 0 | -1 | -1 | 0 | 0 | -1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | -1 |
| K | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | -1 | 0 | 0 |
| L | 0 | 0 | -2 | -1 | 0 | 0 | -1 | 0 | 1 | 0 | 1 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| M | 0 | 0 | -2 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | -1 |
| N | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 |
| P | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | -1 | -1 | 0 |
| Q | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 |
| R | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | -1 | 0 | 0 |
| S | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 |
| T | 0 | 0 | -2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | -1 | 0 | 0 |
| V | 1 | 0 | -1 | -1 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | -1 | 0 | -1 |
| W | -1 | -1 | -3 | -1 | -1 | 0 | -1 | -1 | -1 | -1 | 0 | -1 | -1 | -1 | -1 | -1 | -1 | -1 | -1 | 3 | -1 | -2 |
| Y | 0 | 0 | -2 | -1 | -1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | -1 | 2 | -1 |
| Z | 0 | 2 | -2 | 1 | 0 | -1 | 0 | 0 | -1 | 0 | 0 | -1 | 0 | 0 | 0 | 0 | 0 | 0 | -1 | -2 | -1 | 3 |
Distance Log2 |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 6 | 18 | 8 | 7 | 6 | 7 | 6 | 8 | 6 | 7 | 6 | 8 | 7 | 6 | 7 | 7 | 6 | 6 | 5 | 10 | 8 | 19 |
| B | 18 | 26 | 21 | 17 | 17 | 18 | 17 | 18 | 18 | 17 | 17 | 19 | 17 | 18 | 18 | 17 | 17 | 17 | 17 | 20 | 18 | 27 |
| C | 8 | 21 | 4 | 11 | 10 | 10 | 10 | 11 | 9 | 10 | 9 | 12 | 11 | 10 | 10 | 10 | 9 | 9 | 8 | 13 | 10 | 23 |
| D | 7 | 17 | 11 | 5 | 6 | 8 | 5 | 7 | 8 | 7 | 7 | 9 | 6 | 7 | 7 | 7 | 6 | 6 | 7 | 9 | 8 | 17 |
| E | 6 | 17 | 10 | 6 | 6 | 8 | 6 | 7 | 7 | 6 | 6 | 8 | 6 | 6 | 6 | 6 | 5 | 5 | 6 | 9 | 8 | 18 |
| F | 7 | 18 | 10 | 8 | 8 | 7 | 7 | 9 | 7 | 8 | 6 | 9 | 8 | 8 | 7 | 8 | 7 | 7 | 7 | 9 | 7 | 20 |
| G | 6 | 17 | 10 | 5 | 6 | 7 | 4 | 8 | 8 | 6 | 7 | 9 | 6 | 7 | 6 | 7 | 5 | 6 | 7 | 10 | 7 | 17 |
| H | 8 | 18 | 11 | 7 | 7 | 9 | 8 | 9 | 8 | 7 | 8 | 10 | 8 | 8 | 8 | 7 | 7 | 7 | 8 | 10 | 9 | 20 |
| I | 6 | 18 | 9 | 8 | 7 | 7 | 8 | 8 | 6 | 7 | 5 | 8 | 8 | 7 | 7 | 7 | 7 | 6 | 5 | 9 | 7 | 20 |
| K | 7 | 17 | 10 | 7 | 6 | 8 | 6 | 7 | 7 | 7 | 7 | 9 | 7 | 7 | 7 | 6 | 6 | 6 | 7 | 9 | 8 | 19 |
| L | 6 | 17 | 9 | 7 | 6 | 6 | 7 | 8 | 5 | 7 | 5 | 7 | 7 | 7 | 7 | 7 | 6 | 6 | 5 | 7 | 7 | 19 |
| M | 8 | 19 | 12 | 9 | 8 | 9 | 9 | 10 | 8 | 9 | 7 | 11 | 9 | 9 | 9 | 9 | 8 | 8 | 8 | 11 | 9 | 22 |
| N | 7 | 17 | 11 | 6 | 6 | 8 | 6 | 8 | 8 | 7 | 7 | 9 | 7 | 7 | 7 | 7 | 6 | 6 | 7 | 10 | 8 | 19 |
| P | 6 | 18 | 10 | 7 | 6 | 8 | 7 | 8 | 7 | 7 | 7 | 9 | 7 | 6 | 7 | 7 | 6 | 6 | 6 | 10 | 8 | 19 |
| Q | 7 | 18 | 10 | 7 | 6 | 7 | 6 | 8 | 7 | 7 | 7 | 9 | 7 | 7 | 7 | 7 | 6 | 6 | 7 | 10 | 8 | 19 |
| R | 7 | 17 | 10 | 7 | 6 | 8 | 7 | 7 | 7 | 6 | 7 | 9 | 7 | 7 | 7 | 7 | 6 | 6 | 6 | 9 | 8 | 19 |
| S | 6 | 17 | 9 | 6 | 5 | 7 | 5 | 7 | 7 | 6 | 6 | 8 | 6 | 6 | 6 | 6 | 6 | 5 | 6 | 8 | 7 | 18 |
| T | 6 | 17 | 9 | 6 | 5 | 7 | 6 | 7 | 6 | 6 | 6 | 8 | 6 | 6 | 6 | 6 | 5 | 5 | 5 | 9 | 7 | 19 |
| V | 5 | 17 | 8 | 7 | 6 | 7 | 7 | 8 | 5 | 7 | 5 | 8 | 7 | 6 | 7 | 6 | 6 | 5 | 5 | 8 | 7 | 19 |
| W | 10 | 20 | 13 | 9 | 9 | 9 | 10 | 10 | 9 | 9 | 7 | 11 | 10 | 10 | 10 | 9 | 8 | 9 | 8 | 5 | 9 | 22 |
| Y | 8 | 18 | 10 | 8 | 8 | 7 | 7 | 9 | 7 | 8 | 7 | 9 | 8 | 8 | 8 | 8 | 7 | 7 | 7 | 9 | 5 | 20 |
| Z | 19 | 27 | 23 | 17 | 18 | 20 | 17 | 20 | 20 | 19 | 19 | 22 | 19 | 19 | 19 | 19 | 18 | 19 | 19 | 22 | 20 | 27 |
Distance LN |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 4 | 12 | 5 | 4 | 4 | 5 | 4 | 5 | 4 | 5 | 4 | 6 | 5 | 4 | 5 | 5 | 4 | 4 | 3 | 6 | 5 | 13 |
| B | 12 | 17 | 14 | 11 | 11 | 12 | 11 | 12 | 12 | 12 | 12 | 13 | 12 | 12 | 12 | 12 | 11 | 11 | 12 | 13 | 12 | 18 |
| C | 5 | 14 | 3 | 7 | 7 | 7 | 6 | 7 | 6 | 7 | 6 | 8 | 7 | 7 | 7 | 7 | 6 | 6 | 5 | 9 | 7 | 15 |
| D | 4 | 11 | 7 | 3 | 4 | 5 | 3 | 5 | 5 | 4 | 5 | 6 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 6 | 5 | 11 |
| E | 4 | 11 | 7 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 5 | 4 | 4 | 4 | 4 | 3 | 3 | 4 | 6 | 5 | 12 |
| F | 5 | 12 | 7 | 5 | 5 | 5 | 5 | 6 | 5 | 5 | 4 | 6 | 5 | 5 | 5 | 5 | 4 | 4 | 4 | 6 | 4 | 14 |
| G | 4 | 11 | 6 | 3 | 4 | 5 | 3 | 5 | 5 | 4 | 4 | 6 | 4 | 4 | 4 | 4 | 3 | 4 | 4 | 6 | 5 | 12 |
| H | 5 | 12 | 7 | 5 | 5 | 6 | 5 | 6 | 5 | 5 | 5 | 6 | 5 | 5 | 5 | 5 | 4 | 5 | 5 | 7 | 6 | 13 |
| I | 4 | 12 | 6 | 5 | 5 | 5 | 5 | 5 | 4 | 5 | 3 | 5 | 5 | 4 | 5 | 5 | 4 | 4 | 3 | 6 | 5 | 13 |
| K | 5 | 12 | 7 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 6 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 6 | 5 | 13 |
| L | 4 | 12 | 6 | 5 | 4 | 4 | 4 | 5 | 3 | 4 | 3 | 5 | 5 | 4 | 4 | 4 | 4 | 4 | 3 | 4 | 4 | 13 |
| M | 6 | 13 | 8 | 6 | 5 | 6 | 6 | 6 | 5 | 6 | 5 | 7 | 6 | 6 | 6 | 6 | 5 | 5 | 5 | 7 | 6 | 15 |
| N | 5 | 12 | 7 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 5 | 6 | 5 | 4 | 5 | 4 | 4 | 4 | 4 | 7 | 5 | 13 |
| P | 4 | 12 | 7 | 4 | 4 | 5 | 4 | 5 | 4 | 4 | 4 | 6 | 4 | 4 | 5 | 4 | 4 | 4 | 4 | 6 | 5 | 13 |
| Q | 5 | 12 | 7 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 6 | 5 | 5 | 5 | 4 | 4 | 4 | 4 | 6 | 5 | 13 |
| R | 5 | 12 | 7 | 4 | 4 | 5 | 4 | 5 | 5 | 4 | 4 | 6 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 6 | 5 | 13 |
| S | 4 | 11 | 6 | 4 | 3 | 4 | 3 | 4 | 4 | 4 | 4 | 5 | 4 | 4 | 4 | 4 | 4 | 3 | 4 | 6 | 4 | 12 |
| T | 4 | 11 | 6 | 4 | 3 | 4 | 4 | 5 | 4 | 4 | 4 | 5 | 4 | 4 | 4 | 4 | 3 | 3 | 3 | 6 | 4 | 13 |
| V | 3 | 12 | 5 | 4 | 4 | 4 | 4 | 5 | 3 | 4 | 3 | 5 | 4 | 4 | 4 | 4 | 4 | 3 | 3 | 6 | 4 | 13 |
| W | 6 | 13 | 9 | 6 | 6 | 6 | 6 | 7 | 6 | 6 | 4 | 7 | 7 | 6 | 6 | 6 | 6 | 6 | 6 | 3 | 6 | 15 |
| Y | 5 | 12 | 7 | 5 | 5 | 4 | 5 | 6 | 5 | 5 | 4 | 6 | 5 | 5 | 5 | 5 | 4 | 4 | 4 | 6 | 3 | 14 |
| Z | 13 | 18 | 15 | 11 | 12 | 14 | 12 | 13 | 13 | 13 | 13 | 15 | 13 | 13 | 13 | 13 | 12 | 13 | 13 | 15 | 14 | 18 |
Distance Log10 |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 1 | 5 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| B | 5 | 7 | 6 | 4 | 4 | 5 | 4 | 5 | 5 | 5 | 5 | 5 | 4 | 5 | 5 | 5 | 4 | 4 | 4 | 5 | 5 | 7 |
| C | 2 | 6 | 1 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 3 | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 6 |
| D | 1 | 4 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 4 |
| E | 1 | 4 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| F | 2 | 5 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 5 |
| G | 1 | 4 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 5 |
| H | 2 | 5 | 3 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 5 |
| I | 1 | 5 | 2 | 2 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| K | 1 | 5 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| L | 1 | 5 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 5 |
| M | 2 | 5 | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 6 |
| N | 1 | 4 | 3 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| P | 1 | 5 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| Q | 1 | 5 | 2 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| R | 1 | 5 | 2 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 |
| S | 1 | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 5 |
| T | 1 | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 5 |
| V | 1 | 4 | 2 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 5 |
| W | 2 | 5 | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 6 |
| Y | 2 | 5 | 2 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 5 |
| Z | 5 | 7 | 6 | 4 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 6 | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 6 | 5 | 7 |
Observed Probability of Transition |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 0.72913% | 0.00025% | 0.20947% | 0.42145% | 0.63159% | 0.30193% | 0.79992% | 0.19578% | 0.60990% | 0.35899% | 0.71693% | 0.14118% | 0.35626% | 0.58973% | 0.40669% | 0.39596% | 0.86148% | 0.68830% | 1.54660% | 0.06609% | 0.25453% | 0.00010% |
| B | 0.00025% | 0.00000% | 0.00002% | 0.00039% | 0.00042% | 0.00015% | 0.00041% | 0.00016% | 0.00014% | 0.00031% | 0.00027% | 0.00008% | 0.00035% | 0.00026% | 0.00021% | 0.00028% | 0.00051% | 0.00041% | 0.00033% | 0.00005% | 0.00014% | 0.00000% |
| C | 0.20947% | 0.00002% | 2.72116% | 0.03253% | 0.04054% | 0.04826% | 0.06037% | 0.02121% | 0.07911% | 0.04882% | 0.08363% | 0.01239% | 0.03153% | 0.04564% | 0.04135% | 0.05273% | 0.07987% | 0.08516% | 0.18683% | 0.00728% | 0.03471% | 0.00000% |
| D | 0.42145% | 0.00039% | 0.03253% | 1.14098% | 1.04557% | 0.21646% | 1.15543% | 0.34981% | 0.25716% | 0.52012% | 0.39205% | 0.09866% | 0.80975% | 0.52634% | 0.49616% | 0.46143% | 0.92792% | 0.70003% | 0.44134% | 0.07916% | 0.21458% | 0.00038% |
| E | 0.63159% | 0.00042% | 0.04054% | 1.04557% | 0.74693% | 0.27018% | 0.94464% | 0.38504% | 0.39707% | 0.69485% | 0.58820% | 0.15418% | 0.65696% | 0.62481% | 0.70401% | 0.74368% | 1.31735% | 1.12876% | 0.66180% | 0.10233% | 0.25159% | 0.00023% |
| F | 0.30193% | 0.00015% | 0.04826% | 0.21646% | 0.27018% | 0.27774% | 0.30433% | 0.12717% | 0.39199% | 0.25070% | 0.82869% | 0.10131% | 0.20302% | 0.18825% | 0.28593% | 0.27525% | 0.46666% | 0.44063% | 0.51152% | 0.12872% | 0.48571% | 0.00003% |
| G | 0.79992% | 0.00041% | 0.06037% | 1.15543% | 0.94464% | 0.30433% | 2.27382% | 0.27314% | 0.27086% | 0.60369% | 0.41540% | 0.10701% | 0.72447% | 0.49658% | 0.71603% | 0.50419% | 1.12136% | 0.73758% | 0.53416% | 0.06707% | 0.40246% | 0.00029% |
| H | 0.19578% | 0.00016% | 0.02121% | 0.34981% | 0.38504% | 0.12717% | 0.27314% | 0.09479% | 0.15988% | 0.29484% | 0.24870% | 0.06023% | 0.19646% | 0.18747% | 0.26048% | 0.31228% | 0.42220% | 0.40221% | 0.26308% | 0.04531% | 0.12917% | 0.00005% |
| I | 0.60990% | 0.00014% | 0.07911% | 0.25716% | 0.39707% | 0.39199% | 0.27086% | 0.15988% | 0.69463% | 0.31951% | 1.31996% | 0.20035% | 0.23868% | 0.46935% | 0.29472% | 0.34617% | 0.54153% | 0.64112% | 1.11792% | 0.07761% | 0.30923% | 0.00005% |
| K | 0.35899% | 0.00031% | 0.04882% | 0.52012% | 0.69485% | 0.25070% | 0.60369% | 0.29484% | 0.31951% | 0.46407% | 0.49226% | 0.11683% | 0.44445% | 0.44329% | 0.50968% | 0.88212% | 0.85733% | 0.88132% | 0.51945% | 0.07752% | 0.22956% | 0.00010% |
| L | 0.71693% | 0.00027% | 0.08363% | 0.39205% | 0.58820% | 0.82869% | 0.41540% | 0.24870% | 1.31996% | 0.49226% | 1.84990% | 0.31258% | 0.34165% | 0.47580% | 0.50402% | 0.52339% | 0.82803% | 0.80747% | 1.53756% | 0.51678% | 0.41898% | 0.00010% |
| M | 0.14118% | 0.00008% | 0.01239% | 0.09866% | 0.15418% | 0.10131% | 0.10701% | 0.06023% | 0.20035% | 0.11683% | 0.31258% | 0.02759% | 0.09174% | 0.12009% | 0.11031% | 0.13441% | 0.19345% | 0.24413% | 0.25875% | 0.03199% | 0.07798% | 0.00001% |
| N | 0.35626% | 0.00035% | 0.03153% | 0.80975% | 0.65696% | 0.20302% | 0.72447% | 0.19646% | 0.23868% | 0.44445% | 0.34165% | 0.09174% | 0.36974% | 0.43128% | 0.40282% | 0.43970% | 0.76273% | 0.70017% | 0.48190% | 0.04963% | 0.20326% | 0.00010% |
| P | 0.58973% | 0.00026% | 0.04564% | 0.52634% | 0.62481% | 0.18825% | 0.49658% | 0.18747% | 0.46935% | 0.44329% | 0.47580% | 0.12009% | 0.43128% | 0.77870% | 0.38439% | 0.45872% | 0.78860% | 0.66054% | 0.57853% | 0.06134% | 0.20747% | 0.00010% |
| Q | 0.40669% | 0.00021% | 0.04135% | 0.49616% | 0.70401% | 0.28593% | 0.71603% | 0.26048% | 0.29472% | 0.50968% | 0.50402% | 0.11031% | 0.40282% | 0.38439% | 0.31240% | 0.54067% | 0.77366% | 0.76718% | 0.48270% | 0.06855% | 0.25693% | 0.00008% |
| R | 0.39596% | 0.00028% | 0.05273% | 0.46143% | 0.74368% | 0.27525% | 0.50419% | 0.31228% | 0.34617% | 0.88212% | 0.52339% | 0.13441% | 0.43970% | 0.45872% | 0.54067% | 0.52192% | 0.93152% | 1.05487% | 0.60424% | 0.09351% | 0.26604% | 0.00010% |
| S | 0.86148% | 0.00051% | 0.07987% | 0.92792% | 1.31735% | 0.46666% | 1.12136% | 0.42220% | 0.54153% | 0.85733% | 0.82803% | 0.19345% | 0.76273% | 0.78860% | 0.77366% | 0.93152% | 0.89192% | 1.58531% | 0.94872% | 0.14640% | 0.46382% | 0.00026% |
| T | 0.68830% | 0.00041% | 0.08516% | 0.70003% | 1.12876% | 0.44063% | 0.73758% | 0.40221% | 0.64112% | 0.88132% | 0.80747% | 0.24413% | 0.70017% | 0.66054% | 0.76718% | 1.05487% | 1.58531% | 1.25399% | 1.11605% | 0.12031% | 0.47706% | 0.00012% |
| V | 1.54660% | 0.00033% | 0.18683% | 0.44134% | 0.66180% | 0.51152% | 0.53416% | 0.26308% | 1.11792% | 0.51945% | 1.53756% | 0.25875% | 0.48190% | 0.57853% | 0.48270% | 0.60424% | 0.94872% | 1.11605% | 1.34554% | 0.14796% | 0.41723% | 0.00008% |
| W | 0.06609% | 0.00005% | 0.00728% | 0.07916% | 0.10233% | 0.12872% | 0.06707% | 0.04531% | 0.07761% | 0.07752% | 0.51678% | 0.03199% | 0.04963% | 0.06134% | 0.06855% | 0.09351% | 0.14640% | 0.12031% | 0.14796% | 1.43300% | 0.07704% | 0.00000% |
| Y | 0.25453% | 0.00014% | 0.03471% | 0.21458% | 0.25159% | 0.48571% | 0.40246% | 0.12917% | 0.30923% | 0.22956% | 0.41898% | 0.07798% | 0.20326% | 0.20747% | 0.25693% | 0.26604% | 0.46382% | 0.47706% | 0.41723% | 0.07704% | 1.44530% | 0.00004% |
| Z | 0.00010% | 0.00000% | 0.00000% | 0.00038% | 0.00023% | 0.00003% | 0.00029% | 0.00005% | 0.00005% | 0.00010% | 0.00010% | 0.00001% | 0.00010% | 0.00010% | 0.00008% | 0.00010% | 0.00026% | 0.00012% | 0.00008% | 0.00000% | 0.00004% | 0.00000% |
Expected Probability of Transition |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 0.30313% | 0.00028% | 0.36579% | 0.62924% | 0.70681% | 0.35140% | 0.81414% | 0.24910% | 0.51928% | 0.52161% | 0.82874% | 0.14441% | 0.45733% | 0.51182% | 0.47522% | 0.55416% | 0.87005% | 0.86698% | 0.82850% | 0.26597% | 0.44421% | 0.00012% |
| B | 0.00028% | 0.00000% | 0.00017% | 0.00029% | 0.00033% | 0.00016% | 0.00038% | 0.00011% | 0.00024% | 0.00024% | 0.00039% | 0.00006% | 0.00021% | 0.00024% | 0.00022% | 0.00026% | 0.00041% | 0.00041% | 0.00039% | 0.00012% | 0.00021% | 0.00000% |
| C | 0.36579% | 0.00017% | 0.11035% | 0.37965% | 0.42646% | 0.21202% | 0.49121% | 0.15029% | 0.31331% | 0.31471% | 0.50002% | 0.08713% | 0.27593% | 0.30880% | 0.28673% | 0.33435% | 0.52495% | 0.52309% | 0.49988% | 0.16047% | 0.26802% | 0.00007% |
| D | 0.62924% | 0.00029% | 0.37965% | 0.32654% | 0.73360% | 0.36471% | 0.84499% | 0.25854% | 0.53896% | 0.54138% | 0.86014% | 0.14988% | 0.47466% | 0.53121% | 0.49323% | 0.57516% | 0.90302% | 0.89983% | 0.85989% | 0.27604% | 0.46105% | 0.00013% |
| E | 0.70681% | 0.00033% | 0.42646% | 0.73360% | 0.41202% | 0.40968% | 0.94917% | 0.29041% | 0.60540% | 0.60812% | 0.96619% | 0.16836% | 0.53318% | 0.59670% | 0.55404% | 0.64607% | 1.01435% | 1.01076% | 0.96590% | 0.31008% | 0.51789% | 0.00015% |
| F | 0.35140% | 0.00016% | 0.21202% | 0.36471% | 0.40968% | 0.10184% | 0.47189% | 0.14438% | 0.30098% | 0.30233% | 0.48035% | 0.08370% | 0.26508% | 0.29666% | 0.27545% | 0.32120% | 0.50430% | 0.50251% | 0.48021% | 0.15416% | 0.25747% | 0.00007% |
| G | 0.81414% | 0.00038% | 0.49121% | 0.84499% | 0.94917% | 0.47189% | 0.54665% | 0.33451% | 0.69733% | 0.70046% | 1.11290% | 0.19392% | 0.61414% | 0.68731% | 0.63817% | 0.74417% | 1.16838% | 1.16425% | 1.11258% | 0.35716% | 0.59653% | 0.00017% |
| H | 0.24910% | 0.00011% | 0.15029% | 0.25854% | 0.29041% | 0.14438% | 0.33451% | 0.05117% | 0.21336% | 0.21431% | 0.34051% | 0.05933% | 0.18790% | 0.21029% | 0.19525% | 0.22769% | 0.35748% | 0.35622% | 0.34041% | 0.10928% | 0.18251% | 0.00005% |
| I | 0.51928% | 0.00024% | 0.31331% | 0.53896% | 0.60540% | 0.30098% | 0.69733% | 0.21336% | 0.22239% | 0.44677% | 0.70984% | 0.12369% | 0.39172% | 0.43838% | 0.40704% | 0.47465% | 0.74522% | 0.74259% | 0.70963% | 0.22781% | 0.38048% | 0.00011% |
| K | 0.52161% | 0.00024% | 0.31471% | 0.54138% | 0.60812% | 0.30233% | 0.70046% | 0.21431% | 0.44677% | 0.22439% | 0.71302% | 0.12424% | 0.39347% | 0.44035% | 0.40887% | 0.47678% | 0.74857% | 0.74592% | 0.71281% | 0.22883% | 0.38219% | 0.00011% |
| L | 0.82874% | 0.00039% | 0.50002% | 0.86014% | 0.96619% | 0.48035% | 1.11290% | 0.34051% | 0.70984% | 0.71302% | 0.56643% | 0.19740% | 0.62516% | 0.69963% | 0.64961% | 0.75752% | 1.18933% | 1.18513% | 1.13253% | 0.36357% | 0.60722% | 0.00017% |
| M | 0.14441% | 0.00006% | 0.08713% | 0.14988% | 0.16836% | 0.08370% | 0.19392% | 0.05933% | 0.12369% | 0.12424% | 0.19740% | 0.01720% | 0.10893% | 0.12191% | 0.11319% | 0.13200% | 0.20724% | 0.20651% | 0.19734% | 0.06335% | 0.10581% | 0.00003% |
| N | 0.45733% | 0.00021% | 0.27593% | 0.47466% | 0.53318% | 0.26508% | 0.61414% | 0.18790% | 0.39172% | 0.39347% | 0.62516% | 0.10893% | 0.17249% | 0.38609% | 0.35848% | 0.41803% | 0.65632% | 0.65400% | 0.62497% | 0.20063% | 0.33509% | 0.00009% |
| P | 0.51182% | 0.00024% | 0.30880% | 0.53121% | 0.59670% | 0.29666% | 0.68731% | 0.21029% | 0.43838% | 0.44035% | 0.69963% | 0.12191% | 0.38609% | 0.21604% | 0.40119% | 0.46783% | 0.73451% | 0.73191% | 0.69943% | 0.22453% | 0.37501% | 0.00010% |
| Q | 0.47522% | 0.00022% | 0.28673% | 0.49323% | 0.55404% | 0.27545% | 0.63817% | 0.19525% | 0.40704% | 0.40887% | 0.64961% | 0.11319% | 0.35848% | 0.40119% | 0.18625% | 0.43438% | 0.68200% | 0.67959% | 0.64942% | 0.20848% | 0.34820% | 0.00010% |
| R | 0.55416% | 0.00026% | 0.33435% | 0.57516% | 0.64607% | 0.32120% | 0.74417% | 0.22769% | 0.47465% | 0.47678% | 0.75752% | 0.13200% | 0.41803% | 0.46783% | 0.43438% | 0.25327% | 0.79528% | 0.79247% | 0.75730% | 0.24311% | 0.40604% | 0.00011% |
| S | 0.87005% | 0.00041% | 0.52495% | 0.90302% | 1.01435% | 0.50430% | 1.16838% | 0.35748% | 0.74522% | 0.74857% | 1.18933% | 0.20724% | 0.65632% | 0.73451% | 0.68200% | 0.79528% | 0.62430% | 1.24420% | 1.18898% | 0.38169% | 0.63749% | 0.00018% |
| T | 0.86698% | 0.00041% | 0.52309% | 0.89983% | 1.01076% | 0.50251% | 1.16425% | 0.35622% | 0.74259% | 0.74592% | 1.18513% | 0.20651% | 0.65400% | 0.73191% | 0.67959% | 0.79247% | 1.24420% | 0.61990% | 1.18478% | 0.38034% | 0.63524% | 0.00018% |
| V | 0.82850% | 0.00039% | 0.49988% | 0.85989% | 0.96590% | 0.48021% | 1.11258% | 0.34041% | 0.70963% | 0.71281% | 1.13253% | 0.19734% | 0.62497% | 0.69943% | 0.64942% | 0.75730% | 1.18898% | 1.18478% | 0.56610% | 0.36346% | 0.60705% | 0.00017% |
| W | 0.26597% | 0.00012% | 0.16047% | 0.27604% | 0.31008% | 0.15416% | 0.35716% | 0.10928% | 0.22781% | 0.22883% | 0.36357% | 0.06335% | 0.20063% | 0.22453% | 0.20848% | 0.24311% | 0.38169% | 0.38034% | 0.36346% | 0.05834% | 0.19487% | 0.00005% |
| Y | 0.44421% | 0.00021% | 0.26802% | 0.46105% | 0.51789% | 0.25747% | 0.59653% | 0.18251% | 0.38048% | 0.38219% | 0.60722% | 0.10581% | 0.33509% | 0.37501% | 0.34820% | 0.40604% | 0.63749% | 0.63524% | 0.60705% | 0.19487% | 0.16274% | 0.00009% |
| Z | 0.00012% | 0.00000% | 0.00007% | 0.00013% | 0.00015% | 0.00007% | 0.00017% | 0.00005% | 0.00011% | 0.00011% | 0.00017% | 0.00003% | 0.00009% | 0.00010% | 0.00010% | 0.00011% | 0.00018% | 0.00018% | 0.00017% | 0.00005% | 0.00009% | 0.00000% |
Transition Count |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 40831899 | 14219 | 11730718 | 23601733 | 35369478 | 16908448 | 44796305 | 10964225 | 34155028 | 20104099 | 40148641 | 7906480 | 19951009 | 33025635 | 22775188 | 22173998 | 48243291 | 38545320 | 86610454 | 3701054 | 14253934 | 5584 |
| B | 14219 | 52 | 1097 | 22138 | 23711 | 8418 | 23302 | 9016 | 8098 | 17470 | 15127 | 4488 | 19769 | 15011 | 12129 | 15729 | 29019 | 23100 | 18619 | 2967 | 8276 | 23 |
| C | 11730718 | 1097 | 152386108 | 1821822 | 2270627 | 2703062 | 3381137 | 1188173 | 4430201 | 2734339 | 4683306 | 694003 | 1765673 | 2555916 | 2315840 | 2952875 | 4473018 | 4769241 | 10462638 | 408081 | 1943821 | 393 |
| D | 23601733 | 22138 | 1821822 | 63895589 | 58552516 | 12122157 | 64704681 | 19589495 | 14401231 | 29127075 | 21955028 | 5525434 | 45346703 | 29475276 | 27785648 | 25840498 | 51963872 | 39202380 | 24715483 | 4433174 | 12017025 | 21584 |
| E | 35369478 | 23711 | 2270627 | 58552516 | 41828752 | 15130389 | 52900533 | 21562478 | 22236590 | 38912328 | 32939584 | 8634343 | 36790333 | 34989799 | 39424875 | 41646743 | 73772280 | 63211119 | 37061372 | 5730694 | 14089339 | 12878 |
| F | 16908448 | 8418 | 2703062 | 12122157 | 15130389 | 15553849 | 17043100 | 7121923 | 21951977 | 14039493 | 46407180 | 5673882 | 11369291 | 10542046 | 16012408 | 15414167 | 26133276 | 24675813 | 28645517 | 7208447 | 27200341 | 1952 |
| G | 44796305 | 23302 | 3381137 | 64704681 | 52900533 | 17043100 | 127335046 | 15296409 | 15168589 | 33807205 | 23262797 | 5992828 | 40571119 | 27808713 | 40098316 | 28235277 | 62797113 | 41304891 | 29913441 | 3756156 | 22537996 | 16706 |
| H | 10964225 | 9016 | 1188173 | 19589495 | 21562478 | 7121923 | 15296409 | 5308343 | 8953527 | 16511475 | 13927384 | 3373316 | 11002278 | 10498493 | 14587418 | 17487982 | 23643587 | 22524393 | 14733028 | 2537493 | 7234068 | 3133 |
| I | 34155028 | 8098 | 4430201 | 14401231 | 22236590 | 21951977 | 15168589 | 8953527 | 38900020 | 17892671 | 73918462 | 11219769 | 13366172 | 26284155 | 16504494 | 19385969 | 30326414 | 35903073 | 62604176 | 4346611 | 17317049 | 3280 |
| K | 20104099 | 17470 | 2734339 | 29127075 | 38912328 | 14039493 | 33807205 | 16511475 | 17892671 | 25988270 | 27567023 | 6542643 | 24889851 | 24824606 | 28542257 | 49399544 | 48011008 | 49354314 | 29089534 | 4341553 | 12855864 | 5812 |
| L | 40148641 | 15127 | 4683306 | 21955028 | 32939584 | 46407180 | 23262797 | 13927384 | 73918462 | 27567023 | 103595529 | 17504668 | 19132885 | 26645469 | 28225601 | 29310109 | 46370034 | 45218817 | 86104144 | 28940134 | 23463032 | 5993 |
| M | 7906480 | 4488 | 694003 | 5525434 | 8634343 | 5673882 | 5992828 | 3373316 | 11219769 | 6542643 | 17504668 | 1545528 | 5137930 | 6725318 | 6177417 | 7527439 | 10833397 | 13671499 | 14490227 | 1791755 | 4367150 | 640 |
| N | 19951009 | 19769 | 1765673 | 45346703 | 36790333 | 11369291 | 40571119 | 11002278 | 13366172 | 24889851 | 19132885 | 5137930 | 20705682 | 24152329 | 22558123 | 24623889 | 42713409 | 39210317 | 26986573 | 2779416 | 11382784 | 6105 |
| P | 33025635 | 15011 | 2555916 | 29475276 | 34989799 | 10542046 | 27808713 | 10498493 | 26284155 | 24824606 | 26645469 | 6725318 | 24152329 | 43607834 | 21526496 | 25688775 | 44162227 | 36990997 | 32397935 | 3435486 | 11618635 | 5580 |
| Q | 22775188 | 12129 | 2315840 | 27785648 | 39424875 | 16012408 | 40098316 | 14587418 | 16504494 | 28542257 | 28225601 | 6177417 | 22558123 | 21526496 | 17494934 | 30277973 | 43325363 | 42962515 | 27031529 | 3839099 | 14388237 | 4846 |
| R | 22173998 | 15729 | 2952875 | 25840498 | 41646743 | 15414167 | 28235277 | 17487982 | 19385969 | 49399544 | 29310109 | 7527439 | 24623889 | 25688775 | 30277973 | 29227828 | 52165476 | 59073153 | 33838105 | 5237034 | 14898629 | 5918 |
| S | 48243291 | 29019 | 4473018 | 51963872 | 73772280 | 26133276 | 62797113 | 23643587 | 30326414 | 48011008 | 46370034 | 10833397 | 42713409 | 44162227 | 43325363 | 52165476 | 49948288 | 88778203 | 53128834 | 8198626 | 25974508 | 14889 |
| T | 38545320 | 23100 | 4769241 | 39202380 | 63211119 | 24675813 | 41304891 | 22524393 | 35903073 | 49354314 | 45218817 | 13671499 | 39210317 | 36990997 | 42962515 | 59073153 | 88778203 | 70224103 | 62499757 | 6737783 | 26715891 | 6942 |
| V | 86610454 | 18619 | 10462638 | 24715483 | 37061372 | 28645517 | 29913441 | 14733028 | 62604176 | 29089534 | 86104144 | 14490227 | 26986573 | 32397935 | 27031529 | 33838105 | 53128834 | 62499757 | 75350894 | 8286269 | 23365114 | 4918 |
| W | 3701054 | 2967 | 408081 | 4433174 | 5730694 | 7208447 | 3756156 | 2537493 | 4346611 | 4341553 | 28940134 | 1791755 | 2779416 | 3435486 | 3839099 | 5237034 | 8198626 | 6737783 | 8286269 | 80248705 | 4314797 | 520 |
| Y | 14253934 | 8276 | 1943821 | 12017025 | 14089339 | 27200341 | 22537996 | 7234068 | 17317049 | 12855864 | 23463032 | 4367150 | 11382784 | 11618635 | 14388237 | 14898629 | 25974508 | 26715891 | 23365114 | 4314797 | 80937684 | 2718 |
| Z | 5584 | 23 | 393 | 21584 | 12878 | 1952 | 16706 | 3133 | 3280 | 5812 | 5993 | 640 | 6105 | 5580 | 4846 | 5918 | 14889 | 6942 | 4918 | 520 | 2718 | 24 |
Number of Amino Acids in Alignment |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 48704 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| B | - | 39 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| C | - | - | 28348 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| D | - | - | - | 50846 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| E | - | - | - | - | 57609 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| F | - | - | - | - | - | 29834 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| G | - | - | - | - | - | - | 68904 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| H | - | - | - | - | - | - | - | 20214 | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| I | - | - | - | - | - | - | - | - | 41360 | - | - | - | - | - | - | - | - | - | - | - | - | - |
| K | - | - | - | - | - | - | - | - | - | 42465 | - | - | - | - | - | - | - | - | - | - | - | - |
| L | - | - | - | - | - | - | - | - | - | - | 65868 | - | - | - | - | - | - | - | - | - | - | - |
| M | - | - | - | - | - | - | - | - | - | - | - | 11510 | - | - | - | - | - | - | - | - | - | - |
| N | - | - | - | - | - | - | - | - | - | - | - | - | 37326 | - | - | - | - | - | - | - | - | - |
| P | - | - | - | - | - | - | - | - | - | - | - | - | - | 41765 | - | - | - | - | - | - | - | - |
| Q | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 37983 | - | - | - | - | - | - | - |
| R | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 45830 | - | - | - | - | - | - |
| S | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 71286 | - | - | - | - | - |
| T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 69505 | - | - | - | - |
| V | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 66430 | - | - | - |
| W | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 20342 | - | - |
| Y | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 36209 | - |
| Z | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 21 |
Percentage of Amino Acids in Alignment |
| A | B | C | D | E | F | G | H | I | K | L | M | N | P | Q | R | S | T | V | W | Y | Z | |
| A | 5.45% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| B | - | 0.00% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| C | - | - | 3.17% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| D | - | - | - | 5.69% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| E | - | - | - | - | 6.45% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| F | - | - | - | - | - | 3.34% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| G | - | - | - | - | - | - | 7.72% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| H | - | - | - | - | - | - | - | 2.26% | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| I | - | - | - | - | - | - | - | - | 4.63% | - | - | - | - | - | - | - | - | - | - | - | - | - |
| K | - | - | - | - | - | - | - | - | - | 4.75% | - | - | - | - | - | - | - | - | - | - | - | - |
| L | - | - | - | - | - | - | - | - | - | - | 7.38% | - | - | - | - | - | - | - | - | - | - | - |
| M | - | - | - | - | - | - | - | - | - | - | - | 1.28% | - | - | - | - | - | - | - | - | - | - |
| N | - | - | - | - | - | - | - | - | - | - | - | - | 4.18% | - | - | - | - | - | - | - | - | - |
| P | - | - | - | - | - | - | - | - | - | - | - | - | - | 4.68% | - | - | - | - | - | - | - | - |
| Q | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4.25% | - | - | - | - | - | - | - |
| R | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 5.13% | - | - | - | - | - | - |
| S | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.98% | - | - | - | - | - |
| T | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.78% | - | - | - | - |
| V | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 7.44% | - | - | - |
| W | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 2.27% | - | - |
| Y | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4.05% | - |
| Z | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0.00% |